SCHEMBL3498908

SCHEMBL3498908

O=C1CC(=C2C(=O)c3ccccc3C2=O)c2ccccc21

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.52
KMT2A Q03164 2/20 0.52
CDC25B P30305 1/20 0.52
MAOA P21397 3/20 0.46
MAPT P10636 5/20 0.44
NPC1 O15118 5/20 0.44
RAB9A P51151 5/20 0.44
SMN1; SMN2 Q16637 4/20 0.44
LMNA P02545 3/20 0.44
MAPK1 P28482 3/20 0.44
NPSR1 Q6W5P4 3/20 0.44
BCHE P06276 2/20 0.44
CES1 P23141 2/20 0.44
APAF1 O14727 2/20 0.44
TDP2 O95551 2/20 0.44
S100A4 P26447 2/20 0.44
HTT P42858 2/20 0.44
KDM4E B2RXH2 1/20 0.44
CES2 O00748 1/20 0.44
TERT O14746 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29411070 1.00 MEN1 (0.52) MEN1KMT2ACDC25BMAOAMAPT
SCHEMBL15527779 0.81 MAOA (0.61) MEN1KMT2ACDC25BMAOAMAPT
SCHEMBL12653452 0.77 ACHE (0.50) MEN1KMT2ACDC25BMAOAMAPT
SCHEMBL1670775 0.77 CES1 (0.62) MEN1KMT2ACDC25BMAOAMAPT
SCHEMBL989081 0.76 CES1 (0.75) MEN1KMT2ACDC25BMAOAMAPT
SCHEMBL88188 0.75 CES1 (0.52) MEN1KMT2ACDC25BMAOAMAPT
SCHEMBL29353628 0.75 CES1 (0.52) MEN1KMT2ACDC25BMAOAMAPT
SCHEMBL11290381 0.75 CES1 (0.60) MEN1KMT2ACDC25BMAOAMAPT
SCHEMBL11293121 0.75 CES1 (0.60) MEN1KMT2ACDC25BMAOAMAPT
SCHEMBL11287850 0.75 CES1 (0.60) MEN1KMT2ACDC25BMAOAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9887370-B2 Compound for organic photoelectric device and organic photoelectric device image sensor, and electronic device including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2018-02-06 US disclosed
US-9887370-B2 Compound for organic photoelectric device and organic photoelectric device image sensor, and electronic device including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2018-02-06 US disclosed
US-20160369237-A1 METHODS TO ACCELERATE THE ISOLATION OF NOVEL CELL STRAINS FROM PLURIPOTENT STEM CELLS AND CELLS OBTAINED THEREBY ADVANCED CELL TECH INC (US) 2016-12-22 US disclosed
US-20160181547-A1 COMPOUND FOR ORGANIC PHOTOELECTRIC DEVICE AND ORGANIC PHOTOELECTRIC DEVICE IMAGE SENSOR, AND ELECTRONIC DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2016-06-23 US disclosed
US-9368729-B2 Mixtures for producing photoactive layers for organic solar cells and organic photodetectors BASF SE (DE) 2016-06-14 US disclosed
US-9368729-B2 Mixtures for producing photoactive layers for organic solar cells and organic photodetectors BASF SE (DE) 2016-06-14 US disclosed
EP-2489084-B1 COMPOSITIONS FOR THE PRODUCTION OF PHOTOACTIVE LAYERS FOR ORGANIC SOLAR CELLS AND ORGANIC PHOTO DETECTORS BASF SE (DE) 2015-12-23 EP disclosed
US-20120267579-A1 MIXTURES FOR PRODUCING PHOTOACTIVE LAYERS FOR ORGANIC SOLAR CELLS AND ORGANIC PHOTODETECTORS BASF SE (DE) 2012-10-25 US disclosed
WO-2011045253-A1 MIXTURES FOR PRODUCING PHOTOACTIVE LAYERS FOR ORGANIC SOLAR CELLS AND ORGANIC PHOTODETECTORS BASF SE (DE) 2011-04-21 WO disclosed
US-20100184033-A1 METHODS TO ACCELERATE THE ISOLATION OF NOVEL CELL STRAINS FROM PLURIPOTENT STEM CELLS AND CELLS OBTAINED THEREBY Lineage Cell Therapeutics, Inc. 2010-07-22 US disclosed
US-20080226601-A1 Herpes Virus-Based Compositions and Methods of Use in the Prenatal and Perinatal Periods UNIVERSITY OF ROCHESTER (US) 2008-09-18 US disclosed
EP-1903873-A2 HERPES VIRUS-BASED COMPOSITIONS AND METHODS OF USE IN THE PRENATAL AND PERINATAL PERIODS THE UNIVERSITY OF ROCHESTER (US) 2008-04-02 EP disclosed
US-20080070303-A1 Using myocardial and/or muscle progenitor cells as modeling tool in tissue engineering; regenerative medicine and organ replacement ADVANCED CELL TECHNOLOGY 2008-03-20 US disclosed
WO-2006135602-A2 HERPES VIRUS-BASED COMPOSITIONS AND METHODS OF USE IN THE PRENATAL AND PERINATAL PERIODS UNIVERSITY OF ROCHESTER (US) 2006-12-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160181547-A1 COMPOUND FOR ORGANIC PHOTOELECTRIC DEVICE AND ORGANIC PHOTOELECTRIC DEVICE IMAGE SENSOR, AND ELECTRONIC DEVICE INCLUDING THE SAME PPOX, OCIAD1, PIEZO1 MEN1 1585/4885KMT2A 1893/4885CDC25B 1137/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.