Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TNF | P01375 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | PRKDC | P78527 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18215472 | 0.82 | MAPT (0.51) | ALDH1A1KDM4ENPC1RAB9AMEN1 | |
| SCHEMBL19040594 | 0.82 | MAPT (0.51) | ALDH1A1KDM4ENPC1RAB9AMEN1 | |
| SCHEMBL29494000 | 0.82 | MAPT (0.51) | ALDH1A1KDM4ENPC1RAB9AMEN1 | |
| SCHEMBL4082665 | 0.80 | ALDH1A1 (0.54) | HTTALDH1A1KDM4ETDP1CYP3A4 | |
| SCHEMBL8909083 | 0.80 | SRC (0.52) | HTTALDH1A1KDM4ETDP1RAB9A | |
| SCHEMBL30894819 | 0.79 | CYP3A4 (0.49) | HTTALDH1A1KDM4ETDP1CYP3A4 | |
| SCHEMBL16808914 | 0.79 | CYP3A4 (0.49) | HTTALDH1A1KDM4ETDP1CYP3A4 | |
| SCHEMBL5515200 | 0.78 | ALDH1A1 (0.47) | HTTALDH1A1KDM4ETDP1CYP3A4 | |
| SCHEMBL19548280 | 0.77 | HTT (0.53) | HTTALDH1A1KDM4ETDP1CYP3A4 | |
| SCHEMBL13970898 | 0.77 | CYP3A4 (0.48) | HTTALDH1A1KDM4ETDP1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5670664-A | Photosensitive organic compounds that release carbon monoxide upon illumination | UNIVERSITY OF MARYLAND BIOTECHNOLOGY INSTITUTE (US) | 1997-09-23 | — | — | US | disclosed |