Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPA1 | P15085 | 3/20 | 0.34 |
| ▸ | CPB1 | P15086 | 1/20 | 0.34 |
| ▸ | CPA3 | P15088 | 1/20 | 0.34 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6772665 | 0.74 | — | — | |
| SCHEMBL729746 | 0.73 | MEN1 (0.37) | CYP2C19HIF1ATDP1KDM4EALDH1A1 | |
| SCHEMBL28813721 | 0.71 | — | — | |
| SCHEMBL6771480 | 0.70 | — | — | |
| SCHEMBL6771509 | 0.70 | — | — | |
| SCHEMBL17846594 | 0.70 | L3MBTL1 (0.39) | CPA1CPB1CPA3CPB2CYP2C19 | |
| SCHEMBL730013 | 0.69 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL7081435 | 0.68 | KMT2A (0.37) | KDM4EALDH1A1 | |
| SCHEMBL7260793 | 0.68 | KCNH2 (0.34) | KDM4EALDH1A1 | |
| SCHEMBL7461297 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5693619-A | ENZYME INHIBITORS; ADMINISTERED TO TREAT CONGESTIVE HEART FAILURE AND HYPERTENSION | BOEHRINGER INGELHEIM (CANADA), LTD. (CA) | 1997-12-02 | — | — | US | disclosed |