SCHEMBL89098

SCHEMBL89098

C=CC(N)c1ccccc1O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 1/20 0.46
GABRB2 P47870 1/20 0.46
TSHR P16473 3/20 0.42
ALDH1A1 P00352 4/20 0.38
ALOX15 P16050 3/20 0.38
HPGD P15428 3/20 0.38
HSD17B10 Q99714 3/20 0.38
POLB P06746 2/20 0.38
KDM4E B2RXH2 2/20 0.38
MAPT P10636 2/20 0.38
HIF1A Q16665 2/20 0.38
NPC1 O15118 1/20 0.38
CA12 O43570 1/20 0.38
GMNN O75496 1/20 0.38
EGFR P00533 1/20 0.38
CA2 P00918 1/20 0.38
LMNA P02545 1/20 0.38
FYN P06241 1/20 0.38
CA3 P07451 1/20 0.38
CYP3A4 P08684 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ether SCHEMBL10505755 0.88 TSHR (0.46) GABRA1GABRB2TSHRALDH1A1POLB
SCHEMBL666673 0.84 DPP4 (0.33) TSHRALDH1A1
SCHEMBL2363603 0.83 LMNA (0.42) GABRA1GABRB2TSHRALDH1A1ALOX15
SCHEMBL11126241 0.79 ESR1 (0.38) ALDH1A1ALOX15HSD17B10NPC1CA12
SCHEMBL6536594 0.78 GABRA1 (0.46) GABRA1GABRB2TSHRALDH1A1ALOX15
SCHEMBL2513507 0.78 GABRA1 (0.46) GABRA1GABRB2TSHRALDH1A1ALOX15
SCHEMBL17774719 0.78 CA1 (0.41) TSHRALDH1A1ALOX15HPGDHSD17B10
SCHEMBL5656918 0.77 MEN1 (0.32) ALDH1A1ALOX15HPGDPOLBKDM4E
SCHEMBL7141221 0.77 GABRA1 (0.50) GABRA1GABRB2TSHRALDH1A1ALOX15
SCHEMBL10855944 0.77 GABRA1 (0.50) GABRA1GABRB2TSHRALDH1A1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 631 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230277445-A1 ADHESIVE DRUG CARRIER UMC UTRECHT HOLDING B.V. (NL) 2023-09-07 US claimed
EP-4238582-A2 HYDROGEL FOR IN-VIVO RELEASE OF MEDICATION UMC Utrecht Holding B.V. (NL) 2023-09-06 EP claimed
EP-3983018-B1 HYDROGEL FOR IN-VIVO RELEASE OF MEDICATION UMC UTRECHT HOLDING BV (NL) 2023-06-07 EP claimed
EP-4164642-A1 IMPROVED ADHESIVE DRUG CARRIER UMC Utrecht Holding B.V. (NL) 2023-04-19 EP claimed
CN-115916156-A Improved adhesive drug carrier UMC乌德勒支控股有限公司 2023-04-04 CN claimed
US-20220193254-A1 HYDROGEL FOR IN-VIVO RELEASE OF MEDICATION SENTRYX B.V. (NL) 2022-06-23 US claimed
EP-3983018-A1 HYDROGEL FOR IN-VIVO RELEASE OF MEDICATION UMC Utrecht Holding B.V. (NL) 2022-04-20 EP claimed
US-20220056222-A1 MULTI(METH)ACRYLATE-FUNCTIONALIZED RESINS AS CO-AGENTS FOR CROSSLINKING OF THERMOPLASTIC POLYMERS ARKEMA FRANCE (FR) 2022-02-24 US claimed
CN-113939275-A Hydrogels for in vivo release of drugs UMC乌德勒支控股有限公司 2022-01-14 CN claimed
WO-2021250205-A1 IMPROVED ADHESIVE DRUG CARRIER UMC UTRECHT HOLDING B.V. (NL) 2021-12-16 WO claimed
WO-2003002693-A2 AMINO ALKYLPHENOL EMULSIFIERS FOR AN AQUEOUS HYDROCARBON FUEL THE LUBRIZOL CORPORATION (US) 2003-01-09 WO claimed
US-20020020106-A1 Amino alkylphenol emulsifiers for an aqueous hydrocarbon fuel LUBRIZOL CORPORATION, THE 2002-02-21 US claimed
US-6325887-B1 PREPARING STABLE AQUEOUS DISPERSION OF PARTIALLY AND HOMOGENEOUSLY CROSSLINKED POLYESTER-BASED POLYURETHANE/POLYUREA CONTAINING INTEGRAL EMULSIFIER AND INTERNAL DISPERSION STABILIZER MORTON INTERNATIONAL, INC. 2001-12-04 US claimed
EP-0835282-A1 IMPROVED PHENOLIC SCORCH RETARDERS SARTOMER COMPANY, INC. (US) 1998-04-15 EP claimed
US-5696190-A CURABLE ELASTOMERS MIXED WITH AN ACID SALT OF (DI)ALKYLAMINOALKYL PHENOL SARTOMER COMPANY (US) 1997-12-09 US claimed
WO-1997001597-A1 IMPROVED PHENOLIC SCORCH RETARDERS SARTOMER COMPANY, INC. (US) 1997-01-16 WO claimed
US-4843160-A Preparation of alpha-aminoalkylphenols THE DOW CHEMICAL COMPANY (US) 1989-06-27 US claimed
US-4746754-A Preparation of carbonate diisocyanates and related compounds THE DOW CHEMICAL COMPANY (US) 1988-05-24 US claimed
US-4496763-A Process for the preparation of alkyl-substituted anilines BAYER AKTIENGESELLSCHAFT (DE) 1985-01-29 US claimed
US-4046747-A Additive for improving the adhesion to textiles of hot melt adhesives based on copolyamides CHEMISCHE WERKE HULS AKTIENGESELLSCHAFT (DT) 1977-09-06 US claimed