Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.41 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.40 |
| ▸ | NSD2 | O96028 | 1/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8908075 | 0.84 | LTA4H (0.57) | ACHELTA4HTSHRTDP1MEN1 | |
| SCHEMBL12201054 | 0.81 | CNR2 (0.49) | LTA4HTSHRTDP1MEN1KMT2A | |
| SCHEMBL27827514 | 0.79 | LTA4H (0.55) | ACHELTA4HTSHRTDP1CNR1 | |
| SCHEMBL8061283 | 0.76 | ESR1 (0.54) | ACHELTA4HTSHRMEN1KMT2A | |
| SCHEMBL22725339 | 0.76 | TSPO (0.38) | ACHETSHRTDP1 | |
| SCHEMBL11876060 | 0.76 | ESR2 (0.54) | ACHELTA4HTSHRTDP1MEN1 | |
| SCHEMBL11052720 | 0.74 | LTA4H (0.53) | ACHELTA4HTSHRTDP1MEN1 | |
| SCHEMBL26694572 | 0.74 | LTA4H (0.57) | ACHELTA4HTSHRMEN1KMT2A | |
| SCHEMBL11876127 | 0.73 | BCHE (0.53) | LTA4HTSHRMEN1KMT2A | |
| SCHEMBL14158372 | 0.73 | SMN1; SMN2 (0.44) | TSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5646140-A | CHOLECYSTOKININ ANTAGONIST; APETITE CONTROL | GLAXO WELLCOME INC. (US) | 1997-07-08 | — | — | US | disclosed |