Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | GRM5 | P41594 | 8/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8912621 | 0.87 | GRM5 (0.49) | APPNPC1MAPTKDM4EMEN1 | |
| SCHEMBL3786925 | 0.77 | APP (0.57) | APPNPC1MAPTKDM4EMEN1 | |
| SCHEMBL8577931 | 0.72 | GRM5 (0.61) | APPNPC1MAPTKDM4EALDH1A1 | |
| SCHEMBL1195805 | 0.71 | APP (0.71) | APPNPC1MAPTKDM4EMEN1 | |
| SCHEMBL5141153 | 0.71 | APP (0.55) | APPNPC1MAPTKDM4EMEN1 | |
| SCHEMBL2450399 | 0.71 | APP (0.80) | APPNPC1MAPTKDM4EMEN1 | |
| SCHEMBL5871989 | 0.69 | APP (0.75) | APPNPC1MAPTKDM4EMEN1 | |
| SCHEMBL2114742 | 0.69 | APP (0.75) | APPNPC1MAPTKDM4EMEN1 | |
| SCHEMBL3791702 | 0.69 | APP (0.57) | APPNPC1MAPTKDM4EMEN1 | |
| SCHEMBL3786899 | 0.69 | APP (0.57) | APPNPC1MAPTKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5703378-A | Materials for the scavanging of hydrogen at high temperatures | SANDIA CORPORATION (US) | 1997-12-30 | — | — | US | claimed |
| US-5624598-A | DOUBLE OR TRIPLE BOND HYDROCARBON COMPOUNDS. FOR HYDROGEN SCAVENGERS | SHEPODD TIMOTHY J (US) | 1997-04-29 | — | — | US | claimed |