Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.42 |
| ▸ | NISCH | Q9Y2I1 | 2/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11543855 | 0.80 | SCN4A (0.43) | ALDH1A1ACHENISCHADRA2BCYP1A2 | |
| SCHEMBL29591819 | 0.80 | ALDH1A1 (0.57) | IRAK4ALDH1A1ACHETLR8NISCH | |
| SCHEMBL2069775 | 0.80 | ALDH1A1 (0.57) | IRAK4ALDH1A1ACHETLR8NISCH | |
| SCHEMBL7054838 | 0.75 | ALDH1A1 (0.46) | IRAK4ALDH1A1ACHETLR8NISCH | |
| SCHEMBL28851801 | 0.73 | ALDH1A1 (0.52) | IRAK4ALDH1A1ACHETLR8NISCH | |
| SCHEMBL8909407 | 0.72 | CA4 (0.39) | CYP1A2CYP2C9CYP2C19KDM4EPOLB | |
| SCHEMBL366155 | 0.72 | CA4 (0.39) | CYP1A2CYP2C9CYP2C19KDM4EPOLB | |
| SCHEMBL31433095 | 0.72 | CA1 (0.65) | IRAK4ALDH1A1ACHENISCHADRA2A | |
| SCHEMBL105697 | 0.72 | CA1 (0.65) | IRAK4ALDH1A1ACHENISCHADRA2A | |
| SCHEMBL5412728 | 0.71 | ALDH1A1 (0.44) | IRAK4ALDH1A1ACHETLR8NISCH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5672588-A | Purine derivatives | NOVO NORDISK A/S (DK) | 1997-09-30 | — | — | US | disclosed |
| EP-0603348-A1 | PURINE DERIVATIVES | NOVO NORDISK A/S (DK) | 1994-06-29 | — | — | EP | disclosed |
| WO-1993023418-A1 | PURINE DERIVATIVES | NOVO NORDISK A/S (DK) | 1993-11-25 | — | — | WO | disclosed |