Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | SCN4A | P35499 | 2/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.33 |
| ▸ | DPP4 | P27487 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL366155 | 1.00 | CA4 (0.39) | CA4MAOAPTGS1SCN4ALTA4H | |
| SCHEMBL11547637 | 0.80 | ACHE (0.41) | TSHRPOLB | |
| SCHEMBL9482061 | 0.78 | POLB (0.43) | MAOASCN4APOLBSLC6A4CYP1A2 | |
| SCHEMBL8909089 | 0.78 | ALDH1A1 (0.43) | MAOASLC6A4 | |
| SCHEMBL8909902 | 0.78 | CA4 (0.41) | CA4MAOAPTGS1LTA4HTSHR | |
| SCHEMBL9124739 | 0.78 | ACHE (0.48) | LTA4HPOLBSLC6A4GAA | |
| SCHEMBL527140 | 0.77 | SCN4A (0.36) | CA4MAOASCN4ALTA4HTSHR | |
| SCHEMBL6822836 | 0.77 | CA1 (0.37) | CA4MAOASCN4ALTA4HTSHR | |
| SCHEMBL3575375 | 0.77 | HPGD (0.46) | SLC6A4 | |
| SCHEMBL1454450 | 0.74 | KDM4E (0.40) | CA4MAOAPTGS1LTA4HTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113846069-B | Amphetamine dehydrogenase mutant and application thereof in chiral amine synthesis | 华东理工大学 | 2023-06-27 | — | — | CN | disclosed |
| US-10023886-B2 | (R)-selective amination | PATHEON HOLDINGS I B.V. (NL) | 2018-07-17 | — | — | US | disclosed |
| EP-2593556-B1 | ENZYMATIC METHOD FOR (R)-SELECTIVE AMINATION | DPX HOLDINGS BV (NL) | 2017-08-30 | — | — | EP | disclosed |
| US-20160032335-A1 | (R)- SELECTIVE AMINATION | DPX HOLDINGS B.V. (NL) | 2016-02-04 | — | — | US | disclosed |
| US-5672588-A | Purine derivatives | NOVO NORDISK A/S (DK) | 1997-09-30 | — | — | US | disclosed |
| EP-0603348-A1 | PURINE DERIVATIVES | NOVO NORDISK A/S (DK) | 1994-06-29 | — | — | EP | disclosed |
| WO-1993023418-A1 | PURINE DERIVATIVES | NOVO NORDISK A/S (DK) | 1993-11-25 | — | — | WO | disclosed |