SCHEMBL8910071

SCHEMBL8910071

CCOP(=S)(OCC)c1ccccc1

nearest known ligand 0.60

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.60
ACHE P22303 1/20 0.48
AOX1 Q06278 1/20 0.44
MEN1 O00255 3/20 0.44
KMT2A Q03164 3/20 0.44
NPSR1 Q6W5P4 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.42
KCNH2 Q12809 1/20 0.42
LMNA P02545 3/20 0.41
ALDH1A1 P00352 2/20 0.41
POLB P06746 1/20 0.40
HIF1A Q16665 1/20 0.39
GAA P10253 1/20 0.39
NR1I2 O75469 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11127924 0.86 TSHR (0.47) TSHRACHEAOX1MEN1KMT2A
SCHEMBL11318101 0.86 TSHR (0.47) TSHRACHEAOX1MEN1KMT2A
SCHEMBL11125281 0.84 TSHR (0.46) TSHRMEN1KMT2A
SCHEMBL30749455 0.80 TSHR (0.50) TSHRACHEMEN1KMT2ANPSR1
SCHEMBL10899905 0.78 ACHE (0.46) TSHRACHEAOX1MEN1KMT2A
SCHEMBL10895041 0.78 ACHE (0.46) TSHRACHEAOX1MEN1KMT2A
SCHEMBL10448565 0.78 ACHE (0.46) TSHRACHEAOX1MEN1KMT2A
SCHEMBL11038663 0.78 TSHR (0.41) TSHRACHEAOX1MEN1KMT2A
SCHEMBL11681207 0.78 TSHR (0.41) TSHRACHEAOX1MEN1KMT2A
SCHEMBL11041507 0.77 TSHR (0.40) TSHRACHEAOX1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5689038-A DETOXIFICATION CHEMICAL WAREFARE AGENTS USING ABSORBENTS THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) 1997-11-18 US disclosed
EP-0517317-B1 Polymer process SHELL INT RESEARCH (NL) 1996-01-10 EP disclosed
CN-1067434-A method for producing polymer SHELL INT RESEARCH (NL) 1992-12-30 CN disclosed
EP-0517317-A1 Polymer process SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1992-12-09 EP disclosed
EP-0120981-B1 RESIN ENCAPSULATION TYPE SEMICONDUCTOR DEVICE KABUSHIKI KAISHA TOSHIBA (JP) 1988-10-12 EP disclosed
US-4617584-A GOOD HUMIDITY RESISTANCE, CORROSION RESITANCE; CURED NOVOLAC TYPE EPOXY RESIN, NOVOLAC PHENOLIC RESIN AND ORGANIC PHOSPHOROUS COMPOUND TOKYO SHIBAURA DENKI KABUSHIKI KAISHA (JP) 1986-10-14 US disclosed
EP-0013744-B1 CATALYST AND PROCESS FOR THE POLYMERIZATION OF ALPHA-OLEFINS AND A PROCESS FOR PREPARING AN ALPHA-OLEFIN POLYMERIZATION CATALYST COMPONENT Standard Oil Company (US) 1984-11-07 EP disclosed
EP-0120981-A1 Resin encapsulation type semiconductor device KABUSHIKI KAISHA TOSHIBA (JP) 1984-10-10 EP disclosed
US-4233182-A High activity catalyst for the polymerization of alpha-olefins STANDARD OIL COMPANY (INDIANA) (US) 1980-11-11 US disclosed
US-4233253-A Method for the preparation of metal salts of phosphorus acid esters STANDARD OIL COMPANY (INDIANA) (US) 1980-11-11 US disclosed
EP-0013744-A1 Catalyst and process for the polymerization of alpha-olefins and a process for preparing an alpha-olefin polymerization catalyst component Standard Oil Company (US) 1980-08-06 EP disclosed