SCHEMBL30749455

SCHEMBL30749455

C=C(c1ccccc1)c1ccc(P(=S)(OCC)OCC)cc1

nearest known ligand 0.50

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.50
MEN1 O00255 3/20 0.42
KMT2A Q03164 3/20 0.42
LMNA P02545 2/20 0.41
ALDH1A1 P00352 2/20 0.37
MAPT P10636 1/20 0.37
POLB P06746 1/20 0.35
ACHE P22303 1/20 0.35
GRM2 Q14416 1/20 0.34
ELANE P08246 2/20 0.34
NPSR1 Q6W5P4 1/20 0.34
NR1I2 O75469 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
KCNH2 Q12809 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24371342 0.81 MEN1 (0.49) MEN1KMT2ALMNAALDH1A1MAPT
SCHEMBL8910071 0.80 TSHR (0.60) TSHRMEN1KMT2ALMNAALDH1A1
SCHEMBL31288539 0.78 TSHR (0.54) TSHRMEN1KMT2ALMNAALDH1A1
SCHEMBL31485042 0.73 MEN1 (0.47) TSHRMEN1KMT2AALDH1A1MAPT
Ether SCHEMBL5208110 0.73 MEN1 (0.50) TSHRMEN1KMT2ALMNAALDH1A1
SCHEMBL11318101 0.72 TSHR (0.47) TSHRMEN1KMT2ALMNAALDH1A1
SCHEMBL19220415 0.70 LTA4H (0.57) MEN1KMT2ALMNAMAPTSMN1; SMN2
SCHEMBL894135 0.70 MEN1 (0.65) TSHRMEN1KMT2ALMNAALDH1A1
SCHEMBL11127924 0.69 TSHR (0.47) TSHRMEN1KMT2AALDH1A1ACHE
SCHEMBL28634213 0.69 MEN1 (0.43) MEN1KMT2ALMNAALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260042873-A1 POLYMER BRUSHES WITH CHAIN-ENDS FUNCTIONALIZED WITH METAL COORDINATING TWO HETERO ELEMENTS FOR SELECTIVE SURFACE MODIFICATION MERCK PATENT GMBH (DE) 2026-02-12 US disclosed
EP-4573134-A2 POLYMER BRUSHES WITH CHAIN-ENDS FUNCTIONALIZED WITH METAL COORDINATING TWO HETERO ELEMENTS FOR SELECTIVE SURFACE MODIFICATION Merck Patent GmbH (DE) 2025-06-25 EP disclosed
WO-2024038035-A2 POLYMER BRUSHES WITH CHAIN-ENDS FUNCTIONALIZED WITH METAL COORDINATING TWO HETERO ELEMENTS FOR SELECTIVE SURFACE MODIFICATION MERCK PATENT GMBH (DE) 2024-02-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260042873-A1 POLYMER BRUSHES WITH CHAIN-ENDS FUNCTIONALIZED WITH METAL COORDINATING TWO HETERO ELEMENTS FOR SELECTIVE SURFACE MODIFICATION VSIG8, PCBP1, PICALM TSHR 1141/4885MEN1 3056/4885KMT2A 2500/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.