SCHEMBL8910085

SCHEMBL8910085

CC(O)C1C2CC3CC(C2)CC1C3.OCCC12CCC(CC1)C2

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.33
MEN1 O00255 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL222556 0.77 GRIN2D (0.31)
SCHEMBL679325 0.73 CYP2C9 (0.41)
SCHEMBL25238884 0.65
SCHEMBL237474 0.65 GRIN2D (0.56) KMT2AMEN1
SCHEMBL17161314 0.64 GRIN2D (0.42) KMT2AMEN1
SCHEMBL3612425 0.64 GRIN2D (0.36) KMT2AMEN1
SCHEMBL602384 0.61 GAA (0.44) KMT2AMEN1
SCHEMBL891886 0.61 MEN1 (0.38) KMT2AMEN1
SCHEMBL226326 0.61
SCHEMBL23539449 0.60

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5658923-A USED IN TREATING DISEASES RELATED TO SIGMA-RECEPTOR, SUCH AS SCHIZOPHRENIA ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1997-08-19 US disclosed