Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 13/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.47 |
| ▸ | HPGD | P15428 | 10/20 | 0.47 |
| ▸ | LMNA | P02545 | 6/20 | 0.47 |
| ▸ | HTT | P42858 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 5/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30336869 | 1.00 | KDM4E (0.51) | KDM4ENPSR1TP53ALDH1A1HPGD | |
| SCHEMBL10989399 | 0.88 | KDM4E (0.50) | KDM4ENPSR1TP53ALDH1A1HPGD | |
| SCHEMBL28623030 | 0.86 | ALDH1A1 (0.54) | KDM4ETP53ALDH1A1HPGDLMNA | |
| SCHEMBL30336241 | 0.86 | GALR3 (0.42) | KDM4ENPSR1TP53ALDH1A1HPGD | |
| SCHEMBL30336554 | 0.86 | RAB9A (0.60) | KDM4ENPSR1TP53ALDH1A1HPGD | |
| SCHEMBL28606441 | 0.86 | TP53 (0.43) | KDM4ENPSR1TP53ALDH1A1HPGD | |
| SCHEMBL28609511 | 0.86 | GALR3 (0.42) | KDM4ENPSR1TP53ALDH1A1HPGD | |
| SCHEMBL30336599 | 0.86 | ALDH1A1 (0.54) | KDM4ETP53ALDH1A1HPGDLMNA | |
| SCHEMBL30336637 | 0.86 | TP53 (0.43) | KDM4ENPSR1TP53ALDH1A1HPGD | |
| SCHEMBL28606846 | 0.86 | RAB9A (0.60) | KDM4ENPSR1TP53ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113264934-B | Method for synthesizing 6-alkoxymethyl-benzo [4,5] imidazo [1,2-c ] quinazoline by photocatalysis | 长沙理工大学 | 2023-04-21 | — | — | CN | disclosed |
| CN-113264934-A | Method for synthesizing 6-alkoxymethyl-benzo [4,5] imidazo [1,2-c ] quinazoline by photocatalysis | 长沙理工大学 | 2021-08-17 | — | — | CN | disclosed |
| US-5635525-A | DIAGNOSTICS | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-06-03 | — | — | US | disclosed |
| US-5444068-A | Imidazopyridine derivatives as angiotensin II receptor antagonists, pharmaceuticals, and treatment of hypertension therewith | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-08-22 | — | — | US | disclosed |