Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 5/20 | 0.47 |
| ▸ | CHRNB4 | P30926 | 5/20 | 0.47 |
| ▸ | CHRNA3 | P32297 | 5/20 | 0.47 |
| ▸ | CHRNA7 | P36544 | 5/20 | 0.47 |
| ▸ | CHRNA4 | P43681 | 5/20 | 0.47 |
| ▸ | CHRNA10 | Q9GZZ6 | 4/20 | 0.47 |
| ▸ | CHRNA9 | Q9UGM1 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
| ▸ | YES1 | P07947 | 1/20 | 0.35 |
| ▸ | LYN | P07948 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8683651 | 0.75 | ALDH1A1 (0.57) | CHRNB2CHRNB4CHRNA3CHRNA7CHRNA4 | |
| SCHEMBL851166 | 0.74 | ALDH1A1 (0.66) | ALDH1A1SMN1; SMN2MAPTLMNAHPGD | |
| SCHEMBL8683882 | 0.72 | LTA4H (0.56) | CHRNB2CHRNB4CHRNA3CHRNA7CHRNA4 | |
| SCHEMBL8204708 | 0.72 | ALDH1A1 (0.75) | ALDH1A1SMN1; SMN2MAPTLMNAHPGD | |
| SCHEMBL5090074 | 0.72 | ALDH1A1 (0.75) | ALDH1A1SMN1; SMN2MAPTLMNAHPGD | |
| SCHEMBL8551794 | 0.72 | ALDH1A1 (0.69) | ALDH1A1SMN1; SMN2MAPTLMNAHPGD | |
| SCHEMBL6657819 | 0.71 | ALDH1A1 (0.58) | ALDH1A1SMN1; SMN2MAPTLMNAHPGD | |
| SCHEMBL8373486 | 0.70 | ALDH1A1 (0.67) | ALDH1A1SMN1; SMN2MAPTLMNAHPGD | |
| SCHEMBL8549614 | 0.70 | ALDH1A1 (0.67) | ALDH1A1SMN1; SMN2MAPTLMNAHPGD | |
| SCHEMBL8373505 | 0.70 | ALDH1A1 (0.67) | ALDH1A1SMN1; SMN2MAPTLMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997030709-A1 | BENZOTHIOPHENES, FORMULATIONS CONTAINING SAME, AND METHODS | ELI LILLY AND COMPANY (US) | 1997-08-28 | — | — | WO | disclosed |