Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 18/20 | 0.40 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.38 |
| ▸ | PYGL | P06737 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8909460 | 0.91 | P2RX1 (0.38) | RENP2RX1PYGL | |
| SCHEMBL8909162 | 0.90 | P2RX1 (0.38) | RENP2RX1PYGL | |
| SCHEMBL8910568 | 0.90 | P2RX1 (0.38) | RENP2RX1PYGL | |
| SCHEMBL8911077 | 0.85 | P2RX1 (0.42) | RENP2RX1PYGL | |
| SCHEMBL8910668 | 0.76 | P2RX1 (0.44) | RENP2RX1 | |
| SCHEMBL8910213 | 0.74 | P2RX1 (0.46) | RENP2RX1PYGL | |
| SCHEMBL9800527 | 0.71 | P2RX1 (0.41) | RENP2RX1 | |
| SCHEMBL7290665 | 0.69 | P2RX1 (0.46) | RENP2RX1 | |
| SCHEMBL7433840 | 0.69 | P2RX1 (0.46) | RENP2RX1 | |
| SCHEMBL7277076 | 0.69 | P2RX1 (0.46) | RENP2RX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5688946-A | DIPEPTIDES FOR HYPOTENSIVE AGENTS AND CARDIOVASCULAR DISORDERS | HOFFMANN LA ROCHE INC. (US) | 1997-11-18 | — | — | US | disclosed |