Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX1 | P51575 | 1/20 | 0.44 |
| ▸ | CCR1 | P32246 | 7/20 | 0.38 |
| ▸ | REN | P00797 | 10/20 | 0.37 |
| ▸ | TACR2 | P21452 | 2/20 | 0.34 |
| ▸ | TACR3 | P29371 | 2/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8910213 | 0.79 | P2RX1 (0.46) | P2RX1CCR1REN | |
| SCHEMBL8909162 | 0.78 | P2RX1 (0.38) | P2RX1REN | |
| SCHEMBL8909460 | 0.78 | P2RX1 (0.38) | P2RX1CCR1REN | |
| SCHEMBL8910568 | 0.78 | P2RX1 (0.38) | P2RX1REN | |
| SCHEMBL8911077 | 0.77 | P2RX1 (0.42) | P2RX1CCR1REN | |
| SCHEMBL8910260 | 0.76 | REN (0.40) | P2RX1REN | |
| SCHEMBL9800527 | 0.74 | P2RX1 (0.41) | P2RX1REN | |
| SCHEMBL7290665 | 0.72 | P2RX1 (0.46) | P2RX1REN | |
| SCHEMBL7277076 | 0.72 | P2RX1 (0.46) | P2RX1REN | |
| SCHEMBL7433840 | 0.72 | P2RX1 (0.46) | P2RX1REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5688946-A | DIPEPTIDES FOR HYPOTENSIVE AGENTS AND CARDIOVASCULAR DISORDERS | HOFFMANN LA ROCHE INC. (US) | 1997-11-18 | — | — | US | disclosed |