SCHEMBL8910315

SCHEMBL8910315

CC(=O)Nc1c(I)c(C(=O)N(C)CC(CO)(CO)CO)c(I)c(C(=O)N(C)CC(CO)(CO)CO)c1I

nearest known ligand 0.43

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LMNA P02545 5/20 0.43
SMN1; SMN2 Q16637 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL619808 0.76 LMNA (0.60) LMNASMN1; SMN2
SCHEMBL11546496 0.75 LMNA (0.50) LMNASMN1; SMN2
SCHEMBL8911300 0.75 SMN1; SMN2 (0.49) LMNASMN1; SMN2
SCHEMBL10879331 0.75 LMNA (0.50) LMNASMN1; SMN2
SCHEMBL621840 0.74 LMNA (0.49) LMNASMN1; SMN2
SCHEMBL11694407 0.71 LMNA (0.40) LMNASMN1; SMN2
SCHEMBL11693012 0.71 LMNA (0.49) LMNASMN1; SMN2
SCHEMBL11526230 0.70 SMN1; SMN2 (0.64) LMNASMN1; SMN2
SCHEMBL10878087 0.69 LMNA (0.44) LMNASMN1; SMN2
SCHEMBL9000039 0.69 LMNA (0.58) LMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5609851-A Compounds which can be used in contrast products for radiography GUERBET S A. (FR) 1997-03-11 US disclosed
WO-1993009123-A1 HETEROCYCLIC AMINO-BORANES BORON BIOLOGICALS, INC. (US) 1993-05-13 WO disclosed