Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 2/20 | 0.65 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.65 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.65 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.65 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.65 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.60 |
| ▸ | STAT6 | P42226 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL743588 | 1.00 | NT5E (0.65) | NT5EADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL743589 | 1.00 | NT5E (0.65) | NT5EADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL774632 | 0.93 | ADORA3 (0.64) | NT5EADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL742098 | 0.93 | ADORA3 (0.64) | NT5EADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL740871 | 0.93 | ADORA3 (0.64) | NT5EADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL742097 | 0.93 | ADORA3 (0.64) | NT5EADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL638390 | 0.90 | PGK1 (0.66) | ADORA3ADORA2AADORA1ADORA2BTSHR | |
| SCHEMBL638391 | 0.90 | PGK1 (0.66) | ADORA3ADORA2AADORA1ADORA2BTSHR | |
| SCHEMBL743413 | 0.90 | ADORA2A (0.61) | ADORA3ADORA2AADORA1ADORA2BTSHR | |
| SCHEMBL743414 | 0.90 | ADORA2A (0.61) | ADORA3ADORA2AADORA1ADORA2BTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0603348-A1 | PURINE DERIVATIVES | NOVO NORDISK A/S (DK) | 1994-06-29 | — | — | EP | claimed |
| WO-1993023418-A1 | PURINE DERIVATIVES | NOVO NORDISK A/S (DK) | 1993-11-25 | — | — | WO | claimed |
| US-5672588-A | Purine derivatives | NOVO NORDISK A/S (DK) | 1997-09-30 | — | — | US | disclosed |
| EP-0603348-A1 | PURINE DERIVATIVES | NOVO NORDISK A/S (DK) | 1994-06-29 | — | — | EP | disclosed |
| WO-1993023418-A1 | PURINE DERIVATIVES | NOVO NORDISK A/S (DK) | 1993-11-25 | — | — | WO | disclosed |