SCHEMBL891050

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL891520	0.83	MAOB (0.53)	MAOBPOLBPGRALDH1A1HPGD
	SCHEMBL891452	0.81	MAOB (0.57)	MAOBPOLBPGRKDM4EMAPT
	SCHEMBL890958	0.81	MAOB (0.57)	MAOBPOLBPGRALDH1A1L3MBTL1
	SCHEMBL891410	0.81	MAOB (0.51)	MAOBPOLBPGRFOLH1
	SCHEMBL891123	0.80	CBX7 (0.47)	MAOBPGRKDM4EGAACBX7
	SCHEMBL891345	0.80	MAOB (0.56)	MAOBPOLBALDH1A1HPGDKDM4E
	SCHEMBL891372	0.80	MAOB (0.51)	MAOBPOLBPGRALDH1A1HPGD
	SCHEMBL15282198	0.77	MAOB (0.41)	MAOBPOLBPGRALDH1A1HPGD
	SCHEMBL891186	0.75	MAOB (0.47)	MAOBPOLBALDH1A1HPGDSMN1; SMN2
	SCHEMBL15282243	0.71	MAOA (0.49)	MAOBPGRSMN1; SMN2HSD17B10L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.