SCHEMBL891452

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL890958	0.95	MAOB (0.57)	MAOBPGRPOLBHTR1AHTR1D
	SCHEMBL891520	0.90	MAOB (0.53)	MAOBPGRPOLBMAPTKDM4E
	SCHEMBL891372	0.89	MAOB (0.51)	MAOBPGRPOLBMAPTMAPK1
	SCHEMBL891410	0.87	MAOB (0.51)	MAOBPGRPOLB
	SCHEMBL891123	0.84	CBX7 (0.47)	MAOBPGRHTR1DKDM4E
	SCHEMBL891345	0.81	MAOB (0.56)	MAOBPOLBMAPTKDM4ECYP1A2
	SCHEMBL891050	0.81	MAOB (0.45)	MAOBPGRPOLBMAPTMAPK1
	SCHEMBL15282198	0.78	MAOB (0.41)	MAOBPGRPOLBMAPTMAPK1
	SCHEMBL15282200	0.77	MAOB (0.42)	MAOBPGR
	SCHEMBL15282243	0.77	MAOA (0.49)	MAOBPGRMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.