SCHEMBL8910529

SCHEMBL8910529

CCC(=O)CC=CCC(C)=O

nearest known ligand 0.45

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.45
TDP1 Q9NUW8 2/20 0.45
CYP2D6 P10635 1/20 0.35
ALOX15 P16050 1/20 0.35
FFAR3 O14843 1/20 0.32
TSHR P16473 1/20 0.31
TRPA1 O75762 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16705750 1.00 ALDH1A1 (0.45) ALDH1A1TDP1CYP2D6ALOX15FFAR3
SCHEMBL12572575 0.83 ALDH1A1 (0.47) ALDH1A1TDP1CYP2D6ALOX15FFAR3
SCHEMBL18868445 0.83 ALDH1A1 (0.47) ALDH1A1TDP1CYP2D6ALOX15FFAR3
SCHEMBL9327903 0.81
SCHEMBL11078516 0.81
SCHEMBL16705751 0.81
SCHEMBL16705748 0.79 ALDH1A1 (0.63) ALDH1A1TDP1CYP2D6ALOX15FFAR3
SCHEMBL16705746 0.79 KDM4E (0.42) ALDH1A1TDP1CYP2D6ALOX15TRPA1
SCHEMBL839631 0.78
SCHEMBL801900 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5677322-A THERAPY FOR AGING, DIABETES OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1997-10-14 US disclosed