Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.57 |
| ▸ | PPARG | P37231 | 3/20 | 0.49 |
| ▸ | PPARA | Q07869 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | SYK | P43405 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.46 |
| ▸ | AKT1 | P31749 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | PPARD | Q03181 | 2/20 | 0.44 |
| ▸ | CTSS | P25774 | 3/20 | 0.44 |
| ▸ | CTSK | P43235 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9800592 | 0.83 | CYP1A2 (0.54) | IDO1CYP1A2CYP3A4CYP2D6PRMT1 | |
| SCHEMBL27174920 | 0.77 | IDO1 (0.64) | IDO1PPARGPPARACA12CA1 | |
| SCHEMBL1927129 | 0.77 | IDO1 (0.64) | IDO1PPARGPPARACYP1A2CYP3A4 | |
| SCHEMBL3838871 | 0.77 | CA12 (0.63) | IDO1CA12CA1CA7CA14 | |
| SCHEMBL20907952 | 0.76 | IDO1 (0.63) | IDO1PPARGPPARACA12CA1 | |
| SCHEMBL30621316 | 0.75 | SYK (0.53) | IDO1PPARGPPARACA12CA1 | |
| SCHEMBL16798319 | 0.75 | IDO1 (0.52) | IDO1PPARGPPARACA12CA1 | |
| SCHEMBL30621318 | 0.75 | SYK (0.53) | IDO1PPARGPPARACA12CA1 | |
| Bromide SCHEMBL20898340 | 0.75 | IDO1 (0.62) | IDO1PPARGPPARACA12CA1 | |
| SCHEMBL29026120 | 0.75 | PPARG (0.48) | IDO1PPARGPPARANPSR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5688946-A | DIPEPTIDES FOR HYPOTENSIVE AGENTS AND CARDIOVASCULAR DISORDERS | HOFFMANN LA ROCHE INC. (US) | 1997-11-18 | — | — | US | disclosed |