Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 10/20 | 0.43 |
| ▸ | GGPS1 | O95749 | 7/20 | 0.43 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16360116 | 1.00 | FDPS (0.43) | FDPSGGPS1SMPD1TSHRTHRB | |
| SCHEMBL8910635 | 0.90 | FDPS (0.33) | FDPSGGPS1 | |
| SCHEMBL27408343 | 0.83 | GGPS1 (0.41) | FDPSGGPS1SMPD1TSHRTHRB | |
| SCHEMBL7183712 | 0.79 | FDPS (0.52) | FDPSGGPS1SMPD1CES2 | |
| SCHEMBL11731548 | 0.75 | FDPS (0.46) | FDPSGGPS1SMPD1TSHRTHRB | |
| SCHEMBL11752224 | 0.75 | FDPS (0.46) | FDPSGGPS1SMPD1TSHRTHRB | |
| SCHEMBL29189123 | 0.75 | FDPS (0.46) | FDPSGGPS1SMPD1TSHRTHRB | |
| SCHEMBL9742058 | 0.75 | FDPS (0.46) | FDPSGGPS1SMPD1TSHRTHRB | |
| SCHEMBL10322967 | 0.75 | FDPS (0.46) | FDPSGGPS1SMPD1TSHRTHRB | |
| SCHEMBL6047722 | 0.75 | FDPS (0.46) | FDPSGGPS1SMPD1TSHRTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5693799-A | Method of synthesizing an organophosphorus compound | NOVARTIS CORP. (US) | 1997-12-02 | — | — | US | disclosed |
| US-5488171-A | Phosphinate esters | CIBA-GEIGY CORPORATION (US) | 1996-01-30 | — | — | US | disclosed |
| EP-0614900-A1 | Phosphinate esters | CIBA-GEIGY AG (CH) | 1994-09-14 | — | — | EP | disclosed |