Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRIM58 | Q8NG06 | 5/20 | 0.55 |
| ▸ | VCP | P55072 | 12/20 | 0.48 |
| ▸ | BCDIN3D | Q7Z5W3 | 1/20 | 0.38 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.38 |
| ▸ | TCF7L2 | Q9NQB0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8900442 | 0.84 | TRIM58 (0.48) | TRIM58VCP | |
| SCHEMBL8904733 | 0.81 | TRIM58 (0.56) | TRIM58VCP | |
| SCHEMBL8891165 | 0.81 | TRIM58 (0.55) | TRIM58VCP | |
| SCHEMBL8906282 | 0.81 | TRIM58 (0.56) | TRIM58VCP | |
| SCHEMBL8908523 | 0.79 | TRIM58 (0.53) | TRIM58VCP | |
| SCHEMBL8906810 | 0.79 | TRIM58 (0.52) | TRIM58VCP | |
| SCHEMBL8890942 | 0.77 | VCP (0.48) | TRIM58VCP | |
| SCHEMBL8908526 | 0.72 | TRIM58 (0.45) | TRIM58 | |
| SCHEMBL21055791 | 0.69 | TRIM58 (0.74) | TRIM58CTNNB1TCF7L2 | |
| SCHEMBL13796772 | 0.69 | NPY5R (0.68) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997020823-A2 | 2-AMINO QUINAZOLINE DERIVATIVES AS NPY RECEPTOR ANTAGONISTS | NOVARTIS AG (CH) | 1997-06-12 | — | — | WO | disclosed |