Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 1.00 |
| ▸ | RAB9A | P51151 | 2/20 | 1.00 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.76 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.76 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.76 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.76 |
| ▸ | CGAS | Q8N884 | 1/20 | 0.70 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.52 |
| ▸ | AKT1 | P31749 | 1/20 | 0.52 |
| ▸ | AKT2 | P31751 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | PKLR | P30613 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20579849 | 0.90 | RAB9A (0.82) | NPC1RAB9ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL20579811 | 0.89 | NPC1 (0.80) | NPC1RAB9ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL20579750 | 0.89 | NPC1 (0.79) | NPC1RAB9ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL20579803 | 0.88 | RAB9A (0.79) | NPC1RAB9ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL20579780 | 0.88 | NPC1 (0.78) | NPC1RAB9ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL20579805 | 0.87 | NPC1 (0.77) | NPC1RAB9ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL8912069 | 0.86 | RAB9A (0.76) | NPC1RAB9ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL10675936 | 0.86 | CYP1A2 (1.00) | NPC1RAB9ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL7833938 | 0.84 | CGAS (0.76) | NPC1RAB9ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL20579808 | 0.84 | NPC1 (0.72) | NPC1RAB9ACYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10323033-B2 | Imidazo[1,2-A]pyridine-3-carboxylate derivative and preparation method thereof | KNU-INDUSTRY COOPERATION FOUNDATION (KR) | 2019-06-18 | — | — | US | disclosed |
| US-10323033-B2 | Imidazo[1,2-A]pyridine-3-carboxylate derivative and preparation method thereof | KNU-INDUSTRY COOPERATION FOUNDATION (KR) | 2019-06-18 | — | — | US | disclosed |
| US-20180354948-A1 | IMIDAZO[1,2-A]PYRIDINE-3-CARBOXYLATE DERIVATIVE AND PREPARATION METHOD THEREOF | KNU-INDUSTRY COOPERATION FOUNDATION (KR) | 2018-12-13 | — | — | US | disclosed |
| US-5635525-A | DIAGNOSTICS | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-06-03 | — | — | US | disclosed |
| US-5444068-A | Imidazopyridine derivatives as angiotensin II receptor antagonists, pharmaceuticals, and treatment of hypertension therewith | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-08-22 | — | — | US | disclosed |
| EP-0450566-B1 | Substituted azoles, method for their preparation, these containing compositions and their use | HOECHST AG (DE) | 1995-07-05 | — | — | EP | disclosed |
| EP-0450566-A1 | Substituted azoles, method for their preparation, these containing compositions and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-10-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180354948-A1 | IMIDAZO[1,2-A]PYRIDINE-3-CARBOXYLATE DERIVATIVE AND PREPARATION METHOD THEREOF | AZI2, AOC3, AOC2 | NPC1 4717/4885RAB9A 3999/4885CYP1A2 10/4885 |
| US-10323033-B2 | Imidazo[1,2-A]pyridine-3-carboxylate derivative and preparation method thereof | AZI2, AOC3, AOC2 | NPC1 4717/4885RAB9A 3999/4885CYP1A2 10/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.