Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.58 |
| ▸ | TSHR | P16473 | 6/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.58 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9180847 | 0.93 | ALDH1A1 (0.50) | ALDH1A1TSHRHSD17B10ALOX15SLC2A1 | |
| SCHEMBL4074032 | 0.80 | ALDH1A1 (0.52) | ALDH1A1TSHRHSD17B10ALOX15SLC2A1 | |
| SCHEMBL61574 | 0.78 | SLC2A1 (0.71) | ALDH1A1TSHRHSD17B10ALOX15SLC2A1 | |
| SCHEMBL9626237 | 0.78 | SLC2A1 (0.71) | ALDH1A1TSHRHSD17B10ALOX15SLC2A1 | |
| SCHEMBL27270201 | 0.77 | ALDH1A1 (0.48) | ALDH1A1TSHRHSD17B10ALOX15SLC2A1 | |
| SCHEMBL65261 | 0.76 | ALDH1A1 (1.00) | ALDH1A1TSHRHSD17B10ALOX15SLC2A1 | |
| SCHEMBL346292 | 0.76 | ALDH1A1 (0.61) | ALDH1A1TSHRHSD17B10ALOX15SLC2A1 | |
| SCHEMBL10145543 | 0.76 | ALDH1A1 (0.61) | ALDH1A1TSHRHSD17B10ALOX15SLC2A1 | |
| SCHEMBL3893552 | 0.76 | ALDH1A1 (0.61) | ALDH1A1TSHRHSD17B10ALOX15SLC2A1 | |
| SCHEMBL61350 | 0.75 | SLC2A1 (0.61) | ALDH1A1TSHRHSD17B10ALOX15SLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5622953-A | DRUG RESISTANT TO ANTICANCER CHEMOTHERAPEUTIC DRUG | BASF AKTIENGESELLSCHAFT (DE) | 1997-04-22 | — | — | US | disclosed |
| EP-0691962-A1 | 1-AMINO-3-PHENOXY PROPANE DERIVATIVES AS MODULATORS OF MULTI-DRUG RESISTANCE | BASF AKTIENGESELLSCHAFT (DE) | 1996-01-17 | — | — | EP | disclosed |
| WO-1994022842-A1 | 1-AMINO-3-PHENOXY PROPANE DERIVATIVES AS MODULATORS OF MULTI-DRUG RESISTANCE | BASF AKTIENGESELLSCHAFT (DE) | 1994-10-13 | — | — | WO | disclosed |