SCHEMBL346292

SCHEMBL346292

CC(C)c1ccc(N(C)C)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.61
TSHR P16473 5/20 0.61
ALOX15 P16050 2/20 0.61
HSD17B10 Q99714 2/20 0.61
MAPK1 P28482 4/20 0.55
CYP3A4 P08684 3/20 0.55
TDP1 Q9NUW8 3/20 0.55
TP53 P04637 2/20 0.55
SLC2A1 P11166 2/20 0.50
GAA P10253 2/20 0.46
ATM Q13315 1/20 0.46
L3MBTL1 Q9Y468 2/20 0.45
MAPT P10636 2/20 0.45
CYP1A2 P05177 1/20 0.45
PHLPP2 Q6ZVD8 1/20 0.45
MEN1 O00255 3/20 0.44
KMT2A Q03164 3/20 0.44
MAOA P21397 1/20 0.43
MAOB P27338 1/20 0.43
ADK P55263 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL2861214 0.97 ALDH1A1 (0.58) ALDH1A1TSHRALOX15HSD17B10MAPK1
SCHEMBL13172474 0.93 SLC2A1 (0.61) ALDH1A1TSHRALOX15HSD17B10MAPK1
SCHEMBL14188099 0.93 ALDH1A1 (0.52) ALDH1A1TSHRALOX15HSD17B10MAPK1
SCHEMBL14211473 0.87 RELA (0.61) ALDH1A1ALOX15MAPK1GAAMAPT
SCHEMBL14288344 0.87 ALDH1A1 (0.61) ALDH1A1TSHRALOX15HSD17B10MAPK1
SCHEMBL19786788 0.87 ALDH1A1 (0.46) ALDH1A1TSHRALOX15HSD17B10MAPK1
SCHEMBL21146822 0.87 SLC2A1 (0.55) ALDH1A1TSHRALOX15HSD17B10MAPK1
SCHEMBL2682782 0.87 ALDH1A1 (0.61) ALDH1A1TSHRALOX15HSD17B10MAPK1
SCHEMBL3893552 0.83 ALDH1A1 (0.61) ALDH1A1TSHRALOX15HSD17B10MAPK1
SCHEMBL27269817 0.83 TYR (0.42) ALDH1A1TSHRALOX15HSD17B10MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1160 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6664357-B1 Forming homogeneous mixture of polymerizable (meth)acrylate monomers and oligomers, chelating agent, organic cyclic sulfimide accelerator, heating, adding tertiary amine accelerator, adding photoinitiator at room temperature NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION 2003-12-16 US claimed
EP-0943670-A1 Process for making anaerobic curing adhesive composition National Starch and Chemical Investment Holding Corporation (US) 1999-09-22 EP claimed
US-4235986-A ACRYLATE ESTER MONOMER NATIONAL STARCH AND CHEMICAL CORPORATION (US) 1980-11-25 US claimed
US-20260144714-A1 KIT FOR PREPARING CURABLE COMPOSITION FOR DENTAL MATERIAL, CURABLE COMPOSITION FOR DENTAL MATERIAL, AND DENTAL MATERIAL MITSUI CHEMICALS, INC. (JP) 2026-05-28 US disclosed
US-12622847-B2 Organosilicon compound and dental composition containing same KURARAY NORITAKE DENTAL INC. (JP) 2026-05-12 US disclosed
US-20260124121-A1 POLYMERIZABLE DENTAL COMPOSITION TROETSCHLER TOBIAS (DE) 2026-05-07 US disclosed
EP-4736833-A1 POLYMERIZABLE DENTAL COMPOSITION DENTSPLY SIRONA Inc. (US) 2026-05-06 EP disclosed
EP-3861977-B1 (METH)ACRYLATE, MONOMER COMPOSITION, MOLDED BODY, COMPOSITION FOR DENTAL MATERIAL, AND DENTAL MATERIAL MITSUI CHEMICALS INC (JP) 2026-05-06 EP disclosed
EP-4725470-A1 CURABLE DENTAL COMPOSITION Kuraray Noritake Dental Inc. (JP) 2026-04-15 EP disclosed
US-12564543-B2 Dental composition KURARAY NORITAKE DENTAL INC. (JP) 2026-03-03 US disclosed
US-12527725-B2 Solvent-free dental adhesive composition KURARAY NORITAKE DENTAL INC. (JP) 2026-01-20 US disclosed
EP-1033125-A1 Relining material for dentures KURARAY CO., LTD. (JP) 2000-09-06 EP disclosed
US-6110858-A AN OLEFIN POLYMERIZATION CATALYST CONSISTS OF A TRANSITION METAL COMPOUND, A MODIFIED CLAY COMPOUND CONTAINING CLAY MINERAL AND AN AMINE COMPOUND AND AN ORGANOALUMINUM COMPOUND TOSOH CORPORATION (JP) 2000-08-29 US disclosed
EP-0980682-A1 Bonding compositions for dental use KURARAY CO., LTD. (JP) 2000-02-23 EP disclosed
EP-0948955-A1 POLYMERIZABLE DENTAL COMPOSITION KURARAY CO., LTD. (JP) 1999-10-13 EP disclosed
EP-0943670-A1 Process for making anaerobic curing adhesive composition National Starch and Chemical Investment Holding Corporation (US) 1999-09-22 EP disclosed
EP-0942006-A2 Catalyst for olefin polymer production and process for olefin polymer production employing the catalyst TOSOH CORPORATION (JP) 1999-09-15 EP disclosed
EP-0849292-A1 Olefin polymerisation catalysts and processes for producing olefin polymers TOSOH CORPORATION (JP) 1998-06-24 EP disclosed
US-4235986-A ACRYLATE ESTER MONOMER NATIONAL STARCH AND CHEMICAL CORPORATION (US) 1980-11-25 US disclosed
US-4215209-A ACRYLATE ESTER MONOMER, FREE RADICAL INHIBITOR, CHELATOR AND A SULFONAMIDE OR TERT-AMINE ACCELERATOR NATIONAL STARCH AND CHEMICAL CORPORATION (US) 1980-07-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12527725-B2 Solvent-free dental adhesive composition CDH1, ITGA1, ITGB8 ALDH1A1 1885/4885TSHR 3896/4885ALOX15 153/4885
US-20260144714-A1 KIT FOR PREPARING CURABLE COMPOSITION FOR DENTAL MATERIAL, CURABLE COMPOSITION FOR DENTAL MATERIAL, AND DENTAL MATERIAL CAD, KIT, ILK ALDH1A1 675/4885TSHR 4509/4885ALOX15 1851/4885
US-12564543-B2 Dental composition CAD, ARCN1, MAT1A ALDH1A1 306/4885TSHR 4074/4885ALOX15 1864/4885
US-12622847-B2 Organosilicon compound and dental composition containing same MSL1, ITGA1, ITGAL ALDH1A1 668/4885TSHR 4185/4885ALOX15 2690/4885
US-20260124121-A1 POLYMERIZABLE DENTAL COMPOSITION F12, RAD51, PFN1 ALDH1A1 706/4885TSHR 2717/4885ALOX15 2215/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.