Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 2/20 | 0.50 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.48 |
| ▸ | PSEN1 | P49768 | 3/20 | 0.47 |
| ▸ | PSEN2 | P49810 | 3/20 | 0.47 |
| ▸ | APH1B | Q8WW43 | 3/20 | 0.47 |
| ▸ | NCSTN | Q92542 | 3/20 | 0.47 |
| ▸ | APH1A | Q96BI3 | 3/20 | 0.47 |
| ▸ | PSENEN | Q9NZ42 | 3/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 3/20 | 0.43 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.43 |
| ▸ | BDKRB1 | P46663 | 2/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL197658 | 0.80 | VCAM1 (0.43) | VCAM1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL196414 | 0.80 | VCAM1 (0.43) | VCAM1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL4388495 | 0.80 | VCAM1 (0.43) | VCAM1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL196895 | 0.80 | VCAM1 (0.43) | VCAM1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL8911648 | 0.78 | CNR2 (0.67) | VCAM1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL3844818 | 0.78 | VCAM1 (0.46) | VCAM1CNR2THRBSERPINE1ALDH1A1 | |
| SCHEMBL11740334 | 0.76 | ACLY (0.48) | VCAM1THRB | |
| SCHEMBL9305533 | 0.75 | HTT (0.54) | VCAM1ALDH1A1KMT2A | |
| SCHEMBL10363120 | 0.75 | VCAM1 (0.55) | VCAM1CNR2THRBSERPINE1ALDH1A1 | |
| SCHEMBL26105048 | 0.75 | SERPINE1 (0.50) | VCAM1SERPINE1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5591503-A | Magnetic recording medium having a thin film magnetic layer and a sulfonamide lubricant | THE DOW CHEMICAL COMPANY (US) | 1997-01-07 | — | — | US | claimed |
| WO-1995032500-A1 | SULFONAMIDES USEFUL AS LUBRICANTS IN MAGNETIC RECORDING MEDIA | THE DOW CHEMICAL COMPANY (US) | 1995-11-30 | — | — | WO | claimed |
| US-5591503-A | Magnetic recording medium having a thin film magnetic layer and a sulfonamide lubricant | THE DOW CHEMICAL COMPANY (US) | 1997-01-07 | — | — | US | disclosed |
| WO-1995032500-A1 | SULFONAMIDES USEFUL AS LUBRICANTS IN MAGNETIC RECORDING MEDIA | THE DOW CHEMICAL COMPANY (US) | 1995-11-30 | — | — | WO | disclosed |