Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A1 | O15245 | 3/20 | 0.52 |
| ▸ | DNM1 | Q05193 | 4/20 | 0.50 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.41 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.41 |
| ▸ | FDPS | P14324 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL17529956 | 0.91 | DNM1 (0.65) | SLC22A1DNM1SLC22A2ALDH1A1TP53 | |
| Phosphoric Acid SCHEMBL10632843 | 0.91 | SLC22A1 (0.48) | SLC22A1DNM1SLC22A2ALDH1A1TP53 | |
| Tetrabuthylammonium SCHEMBL19834901 | 0.90 | SLC22A1 (0.67) | SLC22A1DNM1SLC22A2ALDH1A1TP53 | |
| Tetrabuthylammonium SCHEMBL610139 | 0.90 | SLC22A1 (0.67) | SLC22A1DNM1SLC22A2ALDH1A1TP53 | |
| Tetrabuthylammonium SCHEMBL9440008 | 0.90 | SLC22A1 (0.67) | SLC22A1DNM1SLC22A2ALDH1A1TP53 | |
| Tetrabuthylammonium SCHEMBL1049935 | 0.90 | SLC22A1 (0.67) | SLC22A1DNM1SLC22A2ALDH1A1TP53 | |
| Phosphoric Acid SCHEMBL1203423 | 0.88 | DNM1 (0.68) | SLC22A1DNM1SLC22A2ALDH1A1TP53 | |
| Tetrabuthylammonium SCHEMBL29164921 | 0.87 | SLC22A1 (0.63) | SLC22A1DNM1SLC22A2ALDH1A1TP53 | |
| Tetrabuthylammonium SCHEMBL28547697 | 0.87 | SLC22A1 (0.63) | SLC22A1DNM1SLC22A2ALDH1A1TP53 | |
| Tetrabuthylammonium SCHEMBL28973536 | 0.87 | SLC22A1 (0.63) | SLC22A1DNM1SLC22A2ALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5593557-A | ELECTROHYDRODIMERIZATION OF ACRYLONITRILE | BASF AKTIENGESELLSCHAFT (DE) | 1997-01-14 | — | — | US | disclosed |
| US-4789442-A | ELECTROHYDRODIMERIZATION OF ACRYLONITRILE; CORROSION RESISTANCE | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1988-12-06 | — | — | US | disclosed |
| EP-0270390-A2 | A method for producing adiponitrile | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1988-06-08 | — | — | EP | disclosed |