SCHEMBL8911237

SCHEMBL8911237

C(#CC1(C#Cc2ccccc2)C=CC(c2ccccc2)=CC1)c1ccccc1

nearest known ligand 0.34

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
APP P05067 1/20 0.34
MAPT P10636 1/20 0.32
CYP1A1 P04798 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP1B1 Q16678 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4752223 0.78 NOTUM (0.30)
SCHEMBL2428051 0.70 NOTUM (0.33)
SCHEMBL27564610 0.70
Benzene SCHEMBL28178850 0.70 TAAR1 (0.34) MAPTCYP1A2
SCHEMBL1120013 0.70 TAAR1 (0.34) MAPTCYP1A2
SCHEMBL11909980 0.69 APP (0.39) APPMAPTCYP1A2
SCHEMBL28115481 0.69
SCHEMBL21751183 0.69
SCHEMBL27908139 0.69
SCHEMBL2390259 0.68 ALDH1A1 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5703378-A Materials for the scavanging of hydrogen at high temperatures SANDIA CORPORATION (US) 1997-12-30 US claimed
US-5624598-A DOUBLE OR TRIPLE BOND HYDROCARBON COMPOUNDS. FOR HYDROGEN SCAVENGERS SHEPODD TIMOTHY J (US) 1997-04-29 US claimed
US-5703378-A Materials for the scavanging of hydrogen at high temperatures SANDIA CORPORATION (US) 1997-12-30 US disclosed