Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | MAPT | P10636 | 6/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | NMT1 | P30419 | 2/20 | 0.49 |
| ▸ | NMT2 | O60551 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8911758 | 0.85 | AXL (0.62) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL6421455 | 0.84 | MAPT (0.55) | ALDH1A1MAPTSMN1; SMN2MAPK1ATM | |
| SCHEMBL10465583 | 0.83 | ALDH1A1 (0.52) | ALDH1A1MAPTSMN1; SMN2LMNAMAPK1 | |
| SCHEMBL28207288 | 0.81 | MEN1 (0.58) | ALDH1A1MAPTSMN1; SMN2LMNAMAPK1 | |
| SCHEMBL8912395 | 0.81 | DHODH (0.49) | ALDH1A1SMN1; SMN2LMNAKDM4ETP53 | |
| SCHEMBL8966261 | 0.80 | PSMB5 (0.43) | ALDH1A1MAPTSMN1; SMN2LMNAMAPK1 | |
| SCHEMBL2720141 | 0.79 | ALDH1A1 (0.61) | ALDH1A1MAPTSMN1; SMN2LMNAMAPK1 | |
| SCHEMBL9463382 | 0.79 | NR3C2 (0.51) | ALDH1A1MAPTSMN1; SMN2LMNAKDM4E | |
| SCHEMBL31091353 | 0.79 | ALDH1A1 (0.61) | ALDH1A1MAPTSMN1; SMN2LMNAMAPK1 | |
| SCHEMBL9591718 | 0.79 | ALDH1A1 (0.54) | ALDH1A1MAPTSMN1; SMN2LMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5650514-A | 3-substituted quinoline-5-carboxylic acid derivatives and processes for their preparation | BAYER AKTIENGESELLSCHAFT (DE) | 1997-07-22 | — | — | US | disclosed |
| US-5204472-A | For preparing inotropic agents; substituted dihydropyridines | BAYER AKTIENGESELLSCHAFT (DE) | 1993-04-20 | — | — | US | disclosed |
| US-5100900-A | Inotropic agents | BAYER AKTIENGESELLSCHAFT (DE) | 1992-03-31 | — | — | US | disclosed |