Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 3/20 | 0.32 |
| ▸ | CA1 | P00915 | 3/20 | 0.32 |
| ▸ | CA2 | P00918 | 3/20 | 0.32 |
| ▸ | CA9 | Q16790 | 3/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CA3 | P07451 | 2/20 | 0.31 |
| ▸ | CA4 | P22748 | 2/20 | 0.31 |
| ▸ | CA6 | P23280 | 2/20 | 0.31 |
| ▸ | CA5A | P35218 | 2/20 | 0.31 |
| ▸ | CA7 | P43166 | 2/20 | 0.31 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.31 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11381319 | 0.93 | ALDH1A1 (0.42) | ALDH1A1KDM4EHSD17B10L3MBTL1CA12 | |
| SCHEMBL11178469 | 0.91 | ALDH1A1 (0.36) | ALDH1A1KDM4EHSD17B10L3MBTL1LMNA | |
| SCHEMBL11522523 | 0.90 | HTT (0.40) | ALDH1A1KDM4EHSD17B10L3MBTL1CA12 | |
| SCHEMBL10621991 | 0.90 | ALDH1A1 (0.42) | ALDH1A1KDM4EHSD17B10L3MBTL1CA12 | |
| SCHEMBL9787562 | 0.88 | ALDH1A1 (0.36) | ALDH1A1KDM4EHSD17B10L3MBTL1CA12 | |
| SCHEMBL11172819 | 0.83 | BRD4 (0.35) | ALDH1A1KDM4EHSD17B10L3MBTL1LMNA | |
| SCHEMBL6864271 | 0.83 | HTT (0.40) | ALDH1A1KDM4EHSD17B10L3MBTL1CA12 | |
| SCHEMBL11170960 | 0.83 | HPGD (0.43) | ALDH1A1KDM4EHSD17B10CA12CA1 | |
| SCHEMBL11120118 | 0.81 | LMNA (0.35) | ALDH1A1KDM4EHSD17B10L3MBTL1LMNA | |
| SCHEMBL11694667 | 0.81 | APEX1 (0.43) | ALDH1A1KDM4EL3MBTL1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100344606-C | Iodine Ioxilan preparation method | JIANGSU INST OF NUCLEAR MED (CN) | 2007-10-24 | — | — | CN | disclosed |
| US-5609851-A | Compounds which can be used in contrast products for radiography | GUERBET S A. (FR) | 1997-03-11 | — | — | US | disclosed |
| EP-0619744-A4 | NONIONIC X-RAY CONTRAST AGENTS, COMPOSITIONS AND METHODS. | MALLINCKRODT MEDICAL INC (US) | 1995-02-08 | — | — | EP | disclosed |
| EP-0619744-A1 | NONIONIC X-RAY CONTRAST AGENTS, COMPOSITIONS AND METHODS | MALLINCKRODT MEDICAL, INC. (US) | 1994-10-19 | — | — | EP | disclosed |
| WO-1994005337-A1 | NONIONIC X-RAY CONTRAST AGENTS, COMPOSITIONS AND METHODS | MALLINCKRODT MEDICAL, INC. (US) | 1994-03-17 | — | — | WO | disclosed |
| EP-0308364-B1 | Dicarboxylic acid-bis(3,5-dicarbamoyl-2-4-6-triiodanilides), process for their preparation and X-ray contrast agents containing them | SCHERING AG (DE) | 1993-11-10 | — | — | EP | disclosed |
| US-5232685-A | Administering the 5-hydroxyacetamido-triido-isophthalic acid diamide for electroradiography | SCHERING AKTIENGESELLSCHAFT (DE) | 1993-08-03 | — | — | US | disclosed |
| WO-1993010825-A1 | NONIONIC X-RAY CONTRAST AGENTS, COMPOSITIONS AND METHODS | MALLINCKRODT MEDICAL, INC. (US) | 1993-06-10 | — | — | WO | disclosed |
| US-5191120-A | Process for preparing nonionic X-ray contrast agents | MALLINCKRODT MEDICAL, INC. (US) | 1993-03-02 | — | — | US | disclosed |
| US-5183654-A | 5-hydroxyacetamido-2,4,6-tiiodo-isophthalic acid-(2,3-dihydroxy-N-methyl-propyl)-(2-hydroxy-ethyl)-diamide; suitable for accurate diagnosis | SCHERING AKTIENGESELLSCHAFT (DE) | 1993-02-02 | — | — | US | disclosed |
| EP-0504266-A1 | NONIONIC X-RAY CONTRAST AGENTS, COMPOSITIONS AND METHODS | MALLINCKRODT, INC. (US) | 1992-09-23 | — | — | EP | disclosed |
| US-5075502-A | NONIONIC X-RAY CONTRAST AGENTS, COMPOSITIONS AND METHODS | MALLINCKRODT, INC. (US) | 1991-12-24 | — | — | US | disclosed |
| WO-1991009007-A2 | NONIONIC X-RAY CONTRAST AGENTS, COMPOSITIONS AND METHODS | MALLINCKRODT, INC. (US) | 1991-06-27 | — | — | WO | disclosed |
| US-4132731-A | X-RAY CONTRAST AGENT | SCHERING AKTIENGESELLSCHAFT (DE) | 1979-01-02 | — | — | US | disclosed |