Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 9/20 | 0.53 |
| ▸ | HTR2A | P28223 | 6/20 | 0.53 |
| ▸ | HTR2B | P41595 | 6/20 | 0.53 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.45 |
| ▸ | HTR3B | O95264 | 1/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | HTR3A | P46098 | 1/20 | 0.45 |
| ▸ | HTR6 | P50406 | 1/20 | 0.45 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.45 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30593287 | 0.80 | HTR2C (0.54) | HTR2CHTR2AHTR2BHTR3EHTR3B | |
| SCHEMBL6450346 | 0.80 | HTR2C (0.51) | HTR2CHTR2AHTR2BHTR3EHTR3B | |
| SCHEMBL14698726 | 0.80 | HTR2C (0.54) | HTR2CHTR2AHTR2BHTR3EHTR3B | |
| SCHEMBL1074633 | 0.79 | HTR2C (0.47) | HTR2CHTR2AHTR2BDRD2 | |
| SCHEMBL5915126 | 0.78 | DRD2 (0.51) | HTR2CHTR2AHTR2BHTR3EHTR3B | |
| SCHEMBL1944636 | 0.75 | HTR2C (0.52) | HTR2CHTR2AHTR2BMAPTMEN1 | |
| Hydrochloric Acid SCHEMBL10632250 | 0.74 | HTR2C (0.48) | HTR2CHTR2AHTR2BTAAR1 | |
| Hydrochloric Acid SCHEMBL10632262 | 0.74 | HTR2C (0.48) | HTR2CHTR2AHTR2BTAAR1 | |
| Hydrochloric Acid SCHEMBL10632245 | 0.74 | HTR2C (0.48) | HTR2CHTR2AHTR2BTAAR1 | |
| Hydrochloric Acid SCHEMBL10632254 | 0.74 | HTR2C (0.48) | HTR2CHTR2AHTR2BTAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997014419-A1 | TRANSDERMAL DELIVERY OF ALPHA ADRENOCEPTOR BLOCKING AGENTS | FLORA INC. (US) | 1997-04-24 | — | — | WO | disclosed |