Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 9/20 | 0.51 |
| ▸ | HTR2A | P28223 | 6/20 | 0.51 |
| ▸ | HTR2B | P41595 | 6/20 | 0.51 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.40 |
| ▸ | HTR3B | O95264 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | HTR3A | P46098 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.40 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | USP19 | O94966 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30593287 | 0.87 | HTR2C (0.54) | HTR2CHTR2AHTR2BTAAR1HTR3E | |
| SCHEMBL14698726 | 0.87 | HTR2C (0.54) | HTR2CHTR2AHTR2BTAAR1HTR3E | |
| SCHEMBL8911446 | 0.80 | HTR2C (0.53) | HTR2CHTR2AHTR2BTAAR1HTR3E | |
| SCHEMBL5915126 | 0.73 | DRD2 (0.51) | HTR2CHTR2AHTR2BHTR3EHTR3B | |
| SCHEMBL17372630 | 0.72 | HTR2C (0.58) | HTR2CHTR2AHTR2BTAAR1 | |
| Hydrochloric Acid SCHEMBL10632245 | 0.72 | HTR2C (0.48) | HTR2CHTR2AHTR2BTAAR1 | |
| Hydrochloric Acid SCHEMBL10632250 | 0.72 | HTR2C (0.48) | HTR2CHTR2AHTR2BTAAR1 | |
| Hydrochloric Acid SCHEMBL10632254 | 0.72 | HTR2C (0.48) | HTR2CHTR2AHTR2BTAAR1 | |
| Hydrochloric Acid SCHEMBL10632262 | 0.72 | HTR2C (0.48) | HTR2CHTR2AHTR2BTAAR1 | |
| SCHEMBL9527372 | 0.72 | HTR2C (0.46) | HTR2CHTR2AHTR2BTAAR1HTR3E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1581533-A2 | NOVEL BENZONAPHTHYRIDINES | ALTANA Pharma AG (DE) | 2005-10-05 | — | — | EP | claimed |
| WO-2004018465-A9 | BENZONAPHTHYRIDINES WITH PDE 3/4 INHIBITING ACTIVITY | ALTANA PHARMA AG (DE) | 2005-09-15 | — | — | WO | claimed |
| WO-2004018465-A2 | BENZONAPHTHYRIDINES WITH PDE 3/4 INHIBITING ACTIVITY | ALTANA PHARMA AG (DE) | 2004-03-04 | — | — | WO | claimed |
| EP-1581533-A2 | NOVEL BENZONAPHTHYRIDINES | ALTANA Pharma AG (DE) | 2005-10-05 | — | — | EP | disclosed |
| WO-2004018465-A9 | BENZONAPHTHYRIDINES WITH PDE 3/4 INHIBITING ACTIVITY | ALTANA PHARMA AG (DE) | 2005-09-15 | — | — | WO | disclosed |
| WO-2004018465-A2 | BENZONAPHTHYRIDINES WITH PDE 3/4 INHIBITING ACTIVITY | ALTANA PHARMA AG (DE) | 2004-03-04 | — | — | WO | disclosed |