SCHEMBL8911469

SCHEMBL8911469

CC(C#N)C/N=N/C(C)(C)C#N

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2590300 1.00 TSHR (0.32) TSHR
SCHEMBL11809967 0.92 TSHR (0.32) TSHR
SCHEMBL15864178 0.85
SCHEMBL14893216 0.83 TRPA1 (0.31)
SCHEMBL2699502 0.83 TSHR (0.34) TSHR
SCHEMBL11203432 0.83 TRPA1 (0.31)
SCHEMBL6905189 0.83 TSHR (0.34) TSHR
SCHEMBL11357736 0.82
SCHEMBL9005197 0.79
SCHEMBL11364010 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5629395-A THICKENERS SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) 1997-05-13 US claimed
EP-4100381-A1 SUBSTITUTED 1,1'-BIPHENYL COMPOUNDS AND METHODS USING SAME Arbutus Biopharma Corporation (CA) 2022-12-14 EP disclosed
WO-2021158481-A1 SUBSTITUTED 1,1'-BIPHENYL COMPOUNDS AND METHODS USING SAME ARBUTUS BIOPHARMA, INC. (US) 2021-08-12 WO disclosed
US-20140309391-A1 Acryl-based Copolymer Having Superior Heat Resistance and a Method for Manufacturing the Same CHEIL INDUSTRIES INC. (KR) 2014-10-16 US disclosed
US-4696983-A ANTIDEPOSIT AGENTS, CARBOXYL CONTAINING POLYMER AND SURFACTANT THE B. F. GOODRICH COMPANY (US) 1987-09-29 US disclosed
EP-0096392-A1 Novel aminoglycosides, process for production thereof and use thereof KOWA COMPANY, LTD. (JP) 1983-12-21 EP disclosed