Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | AKT1 | P31749 | 2/20 | 0.53 |
| ▸ | ESR1 | P03372 | 1/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.53 |
| ▸ | CDC25A | P30304 | 1/20 | 0.53 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.43 |
| ▸ | PTAFR | P25105 | 1/20 | 0.43 |
| ▸ | HTR1D | P28221 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.43 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.41 |
| ▸ | PRKCG | P05129 | 1/20 | 0.41 |
| ▸ | PRKCB | P05771 | 1/20 | 0.41 |
| ▸ | PRKCA | P17252 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19689041 | 0.80 | LMNA (0.59) | LMNAAKT1ESR1ADORA3CDC25A | |
| SCHEMBL176355 | 0.80 | LMNA (0.56) | LMNAAKT1ESR1ADORA3CDC25A | |
| SCHEMBL3524266 | 0.80 | SMN1; SMN2 (0.48) | LMNAAKT1ESR1ADORA3CDC25A | |
| SCHEMBL8911167 | 0.79 | LMNA (0.58) | LMNAAKT1ESR1ADORA3CDC25A | |
| SCHEMBL8561854 | 0.78 | LMNA (0.61) | LMNAAKT1ESR1ADORA3CDC25A | |
| SCHEMBL1853865 | 0.77 | SMN1; SMN2 (0.70) | LMNAAKT1ESR1ADORA3CDC25A | |
| Phosphocholine SCHEMBL8773459 | 0.77 | SMN1; SMN2 (0.47) | LMNAAKT1ESR1ADORA3CDC25A | |
| SCHEMBL28965396 | 0.76 | SMN1; SMN2 (0.73) | LMNAAKT1ESR1ADORA3CDC25A | |
| Ethylene Glycol SCHEMBL2050406 | 0.76 | SMN1; SMN2 (0.48) | LMNAAKT1ESR1ADORA3CDC25A | |
| Ethylene Glycol SCHEMBL15862264 | 0.76 | SMN1; SMN2 (0.48) | LMNAAKT1ESR1ADORA3CDC25A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5591882-A | Process for preparing organophosphates useful for increasing the ocular haemo- and biocompatibility of synthetic polymers | BIOCOMPATIBLES LIMITED (GB) | 1997-01-07 | — | — | US | disclosed |
| EP-0518959-B1 | METHOD OF IMPROVING THE OCULAR HAEMO AND BIOCOMPATIBILITY OF SYNTHETIC POLYMERS | BIOCOMPATIBLES LTD (GB) | 1996-11-20 | — | — | EP | disclosed |
| US-5422402-A | Surface treatment (of an acrylic, polypropylene, polyethylene, polyurethane, polysaccharide, or cellulosic material) with quaternary ammonium phosphate inner salt having a reactive functional group; contact lenses; blood filtration | BIOCOMPATIBLES LIMITED (GB) | 1995-06-06 | — | — | US | disclosed |
| EP-0518959-A1 | METHOD OF IMPROVING THE OCULAR HAEMO AND BIOCOMPATIBILITY OF SYNTHETIC POLYMERS. | BIOCOMPATIBLES LTD (GB) | 1992-12-23 | — | — | EP | disclosed |
| WO-1991013639-A1 | METHOD OF IMPROVING THE OCULAR HAEMO AND BIOCOMPATIBILITY OF SYNTHETIC POLYMERS | BIOCOMPATIBLES LIMITED (GB) | 1991-09-19 | — | — | WO | disclosed |