Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GYS1 | P13807 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8912763 | 0.93 | HDAC3 (0.30) | — | |
| SCHEMBL7017568 | 0.90 | KDR (0.30) | — | |
| SCHEMBL7024956 | 0.90 | SLC33A1 (0.31) | — | |
| SCHEMBL7021775 | 0.90 | KDR (0.30) | — | |
| SCHEMBL7016267 | 0.89 | PLA2G4A (0.31) | — | |
| SCHEMBL7016263 | 0.89 | PLA2G4A (0.31) | — | |
| SCHEMBL8913862 | 0.88 | MCL1 (0.32) | — | |
| SCHEMBL7017422 | 0.88 | MCL1 (0.32) | — | |
| SCHEMBL7020365 | 0.88 | PTPN11 (0.31) | — | |
| SCHEMBL7021733 | 0.87 | MCL1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5612360-A | AROMATIC N-HETEROCYCLIC COMPOUNDS AS HYPOTENSIVE AGENTS WITH ACID GROUPS, SULFONYLCARBOXAMIDES OR TETRAZOLE GROUPS | ELI LILLY AND COMPANY (US) | 1997-03-18 | — | — | US | disclosed |
| EP-0574174-A2 | Angiotensin II antagonists | ELI LILLY AND COMPANY (US) | 1993-12-15 | — | — | EP | disclosed |