Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.40 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8912130 | 0.94 | CYP11B1 (0.43) | CYP11B1CYP11B2SAE1UBA2MAPT | |
| SCHEMBL8912795 | 0.90 | EPHX2 (0.41) | CYP11B1CYP11B2SAE1UBA2MAPT | |
| SCHEMBL8911091 | 0.87 | ALDH1A1 (0.40) | CYP11B1CYP11B2SAE1UBA2MAPT | |
| SCHEMBL8574886 | 0.84 | ALDH1A1 (0.41) | CYP11B1CYP11B2SAE1UBA2MAPT | |
| SCHEMBL8911321 | 0.84 | PSMB5 (0.43) | CYP11B1CYP11B2SAE1UBA2MAPT | |
| SCHEMBL8910751 | 0.81 | PSMB5 (0.44) | CYP11B1CYP11B2SAE1UBA2MAPT | |
| SCHEMBL8911497 | 0.81 | PSMB5 (0.38) | CYP11B1CYP11B2SAE1UBA2MAPT | |
| SCHEMBL8911251 | 0.79 | FFAR1 (0.39) | CYP11B1CYP11B2MAPTMCHR1KMT2A | |
| SCHEMBL8912348 | 0.79 | CYP11B1 (0.40) | CYP11B1CYP11B2SAE1UBA2MAPT | |
| SCHEMBL8912807 | 0.79 | CYP11B1 (0.44) | CYP11B1CYP11B2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5650424-A | ANTIAGGLOMERANTS USING IMIDAZOLIDINDIONES | DR. KARL THOMAE GMBH (DE) | 1997-07-22 | — | — | US | disclosed |
| US-5478942-A | Antiinflammatory agents, antiagglomerants | KARL THOMAE GMBH (DE) | 1995-12-26 | — | — | US | disclosed |
| US-5276049-A | Treatment of thrombosis | DR. KARL THOMAE GMBH (DE) | 1994-01-04 | — | — | US | disclosed |