Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.44 |
| ▸ | EP300 | Q09472 | 8/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PORCN | Q9H237 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8912511 | 0.94 | CYP11B1 (0.42) | CYP11B1CYP11B2EP300ROCK2KCNH2 | |
| SCHEMBL8912989 | 0.87 | CYP11B1 (0.40) | CYP11B1CYP11B2EP300KCNH2TSHR | |
| SCHEMBL8912130 | 0.85 | CYP11B1 (0.43) | CYP11B1CYP11B2ROCK2MEN1KMT2A | |
| SCHEMBL8911516 | 0.82 | CYP11B1 (0.38) | CYP11B1CYP11B2EP300KCNH2TSHR | |
| SCHEMBL8912795 | 0.79 | EPHX2 (0.41) | CYP11B1CYP11B2ROCK2MEN1KMT2A | |
| SCHEMBL8911515 | 0.79 | CYP11B1 (0.41) | CYP11B1CYP11B2MEN1KMT2A | |
| SCHEMBL8911251 | 0.79 | FFAR1 (0.39) | CYP11B1CYP11B2ROCK2MEN1KMT2A | |
| SCHEMBL8912581 | 0.78 | CYP11B1 (0.37) | CYP11B1CYP11B2EP300MEN1KMT2A | |
| SCHEMBL8911085 | 0.77 | CYP11B1 (0.37) | CYP11B1CYP11B2ROCK2MEN1KMT2A | |
| SCHEMBL8575317 | 0.74 | LIMK1 (0.46) | ROCK2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5650424-A | ANTIAGGLOMERANTS USING IMIDAZOLIDINDIONES | DR. KARL THOMAE GMBH (DE) | 1997-07-22 | — | — | US | disclosed |
| US-5478942-A | Antiinflammatory agents, antiagglomerants | KARL THOMAE GMBH (DE) | 1995-12-26 | — | — | US | disclosed |
| US-5276049-A | Treatment of thrombosis | DR. KARL THOMAE GMBH (DE) | 1994-01-04 | — | — | US | disclosed |