Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLOD2 | O00469 | 3/20 | 0.41 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.36 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.36 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.35 |
| ▸ | CACNA1H | O95180 | 5/20 | 0.34 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.34 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | PLOD3 | O60568 | 2/20 | 0.33 |
| ▸ | PLOD1 | Q02809 | 2/20 | 0.33 |
| ▸ | METAP2 | P50579 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.32 |
| ▸ | FEN1 | P39748 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8913602 | 0.91 | RAB9A (0.39) | PLOD2CACNA1HMEN1KMT2APLOD3 | |
| SCHEMBL8911577 | 0.89 | PLOD2 (0.46) | PLOD2MEN1KMT2APLOD3PLOD1 | |
| SCHEMBL8911624 | 0.86 | RAB9A (0.38) | PLOD2CACNA1HMEN1KMT2APLOD3 | |
| SCHEMBL8912767 | 0.84 | PLOD2 (0.45) | PLOD2MEN1KMT2APLOD3PLOD1 | |
| SCHEMBL8911395 | 0.81 | RAB9A (0.41) | PLOD2CACNA1HMEN1KMT2APLOD3 | |
| SCHEMBL8910998 | 0.79 | PLOD2 (0.41) | PLOD2TAS1R3TAS1R1TAS1R2GPR139 | |
| SCHEMBL8911819 | 0.79 | PLOD2 (0.49) | PLOD2MEN1KMT2APLOD3PLOD1 | |
| SCHEMBL6344726 | 0.78 | ERCC5 (0.50) | PLOD2MEN1KMT2APLOD3PLOD1 | |
| SCHEMBL8911944 | 0.78 | PLOD2 (0.40) | PLOD2PLOD3PLOD1CES2CES1 | |
| SCHEMBL8911872 | 0.78 | PLOD2 (0.47) | PLOD2MEN1KMT2APLOD3PLOD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5618547-A | ADMINISTERING PERFLUOROALKYL GROUP-CONTAINING PHENYL PROPANEDIONE DERIVATIVES | BRITISH TECHNOLOGY GROUP LIMITED (GB) | 1997-04-08 | — | — | US | disclosed |
| US-4870109-A | ANIMAL HUSBANDRY | ELI LILLY AND COMPANY (US) | 1989-09-26 | — | — | US | disclosed |
| EP-0317275-A2 | Control of ectoparasites | BRITISH TECHNOLOGY GROUP USA INC. (US) | 1989-05-24 | — | — | EP | disclosed |