SCHEMBL8911619

SCHEMBL8911619

COC(=O)COC(=O)CNCCNCCNCC(=O)NCCNC(=O)CNCCNCCNCC(=O)O

nearest known ligand 0.37

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CA1 P00915 11/20 0.37
CA2 P00918 11/20 0.37
TSHR P16473 1/20 0.33
ALDH1A1 P00352 1/20 0.33
EGLN1 Q9GZT9 1/20 0.33
RECQL P46063 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20188850 0.78 ALDH1A1 (0.42) CA1CA2ALDH1A1EGLN1
SCHEMBL8911606 0.74 CA1 (0.34) CA1CA2TSHR
SCHEMBL15393662 0.70 CA1 (0.48) CA1CA2TSHRALDH1A1
SCHEMBL8912432 0.69 CA1 (0.33) CA1CA2
SCHEMBL13336065 0.68 CA1 (0.45) CA1CA2ALDH1A1EGLN1
SCHEMBL2303378 0.68 TSHR (0.52) CA1CA2TSHRALDH1A1EGLN1
SCHEMBL2361759 0.68 TSHR (0.50) CA2TSHRALDH1A1RECQL
SCHEMBL8991694 0.68 ALDH1A1 (0.54) TSHRALDH1A1
SCHEMBL27045412 0.68 CA1 (0.43) CA1CA2ALDH1A1EGLN1
SCHEMBL18160753 0.67 LMNA (0.41) CA1CA2TSHREGLN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5679810-A AMIDE OR ESTER LINKAGES; COMPLEXES PARAMAGNETIC METAL IONS; DIAGNOSTIC IMAGING SALUTAR, INC. (US) 1997-10-21 US disclosed