Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.39 |
| ▸ | CES1 | P23141 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8912061 | 0.97 | CES2 (0.39) | CES2CES1KDM4EMEN1NPC1 | |
| SCHEMBL10560273 | 0.82 | RAB9A (0.41) | MEN1NPC1MAPTKMT2A | |
| SCHEMBL19367869 | 0.75 | CES1 (0.59) | CES2CES1KDM4EMEN1NPC1 | |
| SCHEMBL8910968 | 0.73 | CES2 (0.39) | CES2CES1KDM4EMEN1NPC1 | |
| SCHEMBL7220761 | 0.70 | CES1 (0.52) | CES2CES1KDM4EMEN1NPC1 | |
| SCHEMBL976560 | 0.68 | PTPN1 (0.61) | CES2CES1PTPN1HCAR1 | |
| SCHEMBL4457800 | 0.66 | CES2 (0.46) | CES2CES1KDM4EMEN1NPC1 | |
| SCHEMBL363750 | 0.65 | CES2 (0.56) | CES2CES1NPC1SLC6A3PTPN1 | |
| SCHEMBL4361178 | 0.65 | CES2 (0.56) | CES2CES1KDM4EMEN1NPC1 | |
| SCHEMBL20259927 | 0.65 | CES2 (0.45) | CES2CES1KDM4EMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5618547-A | ADMINISTERING PERFLUOROALKYL GROUP-CONTAINING PHENYL PROPANEDIONE DERIVATIVES | BRITISH TECHNOLOGY GROUP LIMITED (GB) | 1997-04-08 | — | — | US | disclosed |
| US-4870109-A | ANIMAL HUSBANDRY | ELI LILLY AND COMPANY (US) | 1989-09-26 | — | — | US | disclosed |
| EP-0317275-A2 | Control of ectoparasites | BRITISH TECHNOLOGY GROUP USA INC. (US) | 1989-05-24 | — | — | EP | disclosed |