SCHEMBL8911683

SCHEMBL8911683

CCCCc1nc2cccc(C(=O)OC)c2n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)NCC2CC2)cc1

nearest known ligand 0.62

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
AGTR2 P50052 9/20 0.62
AGTR1 P30556 6/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8911867 0.93 AGTR2 (0.67) AGTR2AGTR1
SCHEMBL8910603 0.91 AGTR2 (0.63) AGTR2AGTR1
SCHEMBL8911852 0.91 AGTR2 (0.64) AGTR2AGTR1
SCHEMBL9571763 0.89 AGTR2 (0.60) AGTR2AGTR1
SCHEMBL9571737 0.88 AGTR2 (0.63) AGTR2AGTR1
SCHEMBL8910935 0.88 AGTR1 (0.54) AGTR2AGTR1
SCHEMBL8910295 0.86 AGTR1 (0.58) AGTR2AGTR1
SCHEMBL8911632 0.84 AGTR2 (0.69) AGTR2AGTR1
SCHEMBL7025511 0.83 AGTR2 (0.70) AGTR2AGTR1
SCHEMBL9127676 0.81 AGTR1 (0.42) AGTR2AGTR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5635525-A DIAGNOSTICS HOECHST AKTIENGESELLSCHAFT (DE) 1997-06-03 US disclosed
US-5444068-A Imidazopyridine derivatives as angiotensin II receptor antagonists, pharmaceuticals, and treatment of hypertension therewith HOECHST AKTIENGESELLSCHAFT (DE) 1995-08-22 US disclosed