Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 1/20 | 0.51 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.45 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.45 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.45 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.43 |
| ▸ | IDH1 | O75874 | 1/20 | 0.43 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.42 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.42 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.42 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.42 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8130929 | 0.83 | PGR (0.47) | PGRCRBNPDE3BPDE3ATBXAS1 | |
| Hydrochloric Acid SCHEMBL8200981 | 0.81 | SLC22A6 (0.45) | PGRCRBNPDE3BPDE3ATBXAS1 | |
| Hydrochloric Acid SCHEMBL8138996 | 0.80 | SLC22A6 (0.44) | PGRCRBNPDE3BPDE3ATBXAS1 | |
| Hydrochloric Acid SCHEMBL8200679 | 0.79 | SLC22A6 (0.43) | PGRCRBNPDE3BPDE3ATBXAS1 | |
| SCHEMBL21676341 | 0.79 | GRIK1 (0.52) | PGRCRBNPDE3BPDE3ATBXAS1 | |
| Hydrochloric Acid SCHEMBL8145152 | 0.78 | PGR (0.43) | PGRCRBNPDE3BPDE3ATBXAS1 | |
| Hydrochloric Acid SCHEMBL8203289 | 0.78 | SLC22A6 (0.43) | PGRCRBNPDE3BPDE3ATBXAS1 | |
| SCHEMBL7969712 | 0.78 | PGR (0.47) | PGRCRBNPDE3BPDE3ATBXAS1 | |
| Hydrochloric Acid SCHEMBL8200921 | 0.77 | SLC22A6 (0.42) | PGRIDH1CHEK1 | |
| Hydrochloric Acid SCHEMBL8201434 | 0.77 | SLC22A6 (0.42) | PGRIDH1CHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0698024-B1 | [1,2,4]TRIAZOLO [4,3-a]QUINOXALINE COMPOUNDS, THEIR PREPARATION AND USE | NOVO NORDISK AS (DK) | 1997-01-22 | — | — | EP | disclosed |
| US-5532236-A | TREATMENT OF PARKINSON'S DISEASE | NOVO NORDISK A/S (DK) | 1996-07-02 | — | — | US | disclosed |
| EP-0698024-A1 | 1,2,4]TRIAZOLO 4,3-a]QUINOXALINE COMPOUNDS, THEIR PREPARATION AND USE | NOVO NORDISK AS (DK) | 1996-02-28 | — | — | EP | disclosed |
| WO-1994026746-A1 | [1,2,4]TRIAZOLO[4,3-a]QUINOXALINE COMPOUNDS, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1994-11-24 | — | — | WO | disclosed |