Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 1/20 | 0.47 |
| ▸ | PDE3B | Q13370 | 3/20 | 0.44 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.44 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.44 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.44 |
| ▸ | IDH1 | O75874 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.42 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.41 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | PDE2A | O00408 | 2/20 | 0.40 |
| ▸ | PDE1A | P54750 | 1/20 | 0.39 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.39 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.39 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.39 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.39 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7268865 | 0.81 | GRIA1 (0.53) | PGRPDE3BPDE3ACRBNTBXAS1 | |
| SCHEMBL7269285 | 0.78 | PGR (0.44) | PGRPDE3BPDE3ACRBNTBXAS1 | |
| SCHEMBL8911996 | 0.78 | PGR (0.51) | PGRPDE3BPDE3ACRBNTBXAS1 | |
| SCHEMBL21676341 | 0.78 | GRIK1 (0.52) | PGRPDE3BPDE3ACRBNTBXAS1 | |
| Hydrochloric Acid SCHEMBL8130929 | 0.77 | PGR (0.47) | PGRPDE3BPDE3ACRBNTBXAS1 | |
| SCHEMBL7268386 | 0.76 | PDE4A (0.51) | PGRPDE3BPDE3ACRBNTBXAS1 | |
| SCHEMBL2468642 | 0.75 | DAO (0.46) | — | |
| SCHEMBL7982949 | 0.75 | GABRA5 (0.36) | CHEK1GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL29235466 | 0.75 | TP53 (0.46) | CHEK1IDO1 | |
| SCHEMBL7980241 | 0.75 | DAO (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235740-B1 | AUTOIMMUNE DISEASES; ANTIPROLIFERATION AGENTS | BRISTOL-MYERS SQUIBB CO. | 2001-05-22 | — | — | US | disclosed |