Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 2/20 | 0.40 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.37 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.37 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.37 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.37 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 3/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.34 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.34 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.34 |
| ▸ | PTGES | O14684 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | CTSG | P08311 | 1/20 | 0.33 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.33 |
| ▸ | CMA1 | P23946 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8911994 | 0.85 | PLA2G2A (0.38) | TK1PLA2G2APLA2G10PLA2G1BPLA2G5 | |
| SCHEMBL9051162 | 0.85 | TK1 (0.48) | TK1PLA2G2APLA2G10PLA2G1BPLA2G5 | |
| SCHEMBL10928636 | 0.85 | TK1 (0.48) | TK1PLA2G2APLA2G10PLA2G1BPLA2G5 | |
| SCHEMBL29193122 | 0.85 | TK1 (0.48) | TK1PLA2G2APLA2G10PLA2G1BPLA2G5 | |
| SCHEMBL10796162 | 0.85 | TK1 (0.48) | TK1PLA2G2APLA2G10PLA2G1BPLA2G5 | |
| SCHEMBL12978112 | 0.85 | TK1 (0.48) | TK1PLA2G2APLA2G10PLA2G1BPLA2G5 | |
| SCHEMBL10802141 | 0.85 | TK1 (0.48) | TK1PLA2G2APLA2G10PLA2G1BPLA2G5 | |
| SCHEMBL12978102 | 0.85 | TK1 (0.48) | TK1PLA2G2APLA2G10PLA2G1BPLA2G5 | |
| SCHEMBL8734284 | 0.85 | TK1 (0.48) | TK1PLA2G2APLA2G10PLA2G1BPLA2G5 | |
| SCHEMBL29193123 | 0.85 | TK1 (0.48) | TK1PLA2G2APLA2G10PLA2G1BPLA2G5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5614548-A | TREATING TUMORS AND HIV INFECTION, PROTEIN KINASE C INHIBITORS | WAKE FOREST UNIVERSITY (US) | 1997-03-25 | — | — | US | disclosed |