SCHEMBL8912

SCHEMBL8912

OB(O)c1ccc(O)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ENPP2 Q13822 6/20 1.00
CA2 P00918 5/20 0.55
CA1 P00915 4/20 0.55
LPL P06858 2/20 0.55
LIPG Q9Y5X9 2/20 0.55
TSHR P16473 1/20 0.55
CA4 P22748 2/20 0.53
CA5A P35218 2/20 0.53
CA14 Q9ULX7 2/20 0.53
CA5B Q9Y2D0 2/20 0.53
KDM4E B2RXH2 2/20 0.53
MEN1 O00255 1/20 0.53
NPC1 O15118 1/20 0.53
CA12 O43570 1/20 0.53
GMNN O75496 1/20 0.53
ALDH1A1 P00352 1/20 0.53
LMNA P02545 1/20 0.53
CA3 P07451 1/20 0.53
CYP3A4 P08684 1/20 0.53
MAPT P10636 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28105638 0.97 ENPP2 (0.94) ENPP2CA2CA1LPLLIPG
Ammonia Solution, Strong SCHEMBL28882560 0.97 ENPP2 (0.94) ENPP2CA2CA1LPLLIPG
SCHEMBL22361777 0.91 ENPP2 (0.83) ENPP2CA2CA1LPLLIPG
SCHEMBL18459963 0.91 ENPP2 (0.83) ENPP2CA2CA1LPLLIPG
SCHEMBL204921 0.86 ENPP2 (0.73) ENPP2CA2CA1LPLLIPG
SCHEMBL17476000 0.84 ENPP2 (0.71) ENPP2CA2CA1LPLLIPG
SCHEMBL14165789 0.84 ENPP2 (0.71) ENPP2CA2CA1MEN1KMT2A
SCHEMBL15483207 0.84 TTR (0.73) ENPP2CA2CA1CA4CA5A
SCHEMBL29071488 0.83 MGLL (0.82) ENPP2CA2CA1CA4CA5A
SCHEMBL15483227 0.83 ENPP2 (0.68) ENPP2CA2CA1TSHRCA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4890 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4302831-B1 PROCESS FOR SYNTHESIS OF TIRBANIBULIN TRIFARMA S P A (IT) 2025-08-27 EP claimed
US-20250194617-A1 Materials and Methods for Extending Shelf-Life of Foods JP LABORATORIES, INC. 2025-06-19 US claimed
US-20250177537-A1 AN ANTIBIOTIC, METHOD OF PREPARATION AND METHOD OF TREATMENT THEREOF NATIONAL TAIWAN UNIVERSITY (TW) 2025-06-05 US claimed
CN-120081836-A Response near infrared fluorescent probe targeting butyrylcholinesterase and beta amyloid, and preparation method and application thereof 湖北大学 2025-06-03 CN claimed
CN-120058757-A Synthesis method of methyl iminodiacetic acid borate compound 上海泰坦科技股份有限公司 2025-05-30 CN claimed
US-20250169514-A1 Materials and Methods for Extending Shelf-Life of Foods JP LABORATORIES, INC. 2025-05-29 US claimed
CN-119930568-A Galanthamine intermediate compound and its synthesis process 广东东阳光药业股份有限公司 2025-05-06 CN claimed
CN-119751429-A Fluorescent probe with pH value and viscosity response functions and preparation and application thereof 贵州医科大学 2025-04-04 CN claimed
CN-119758664-A Novel dry film for bearing for producing single-sided sheet and application method thereof 苏州东山精密制造股份有限公司 2025-04-04 CN claimed
CN-117672610-B Fireproof communication cable for radiation-resistant nuclear power station and preparation method thereof 江苏赛德电气有限公司 2025-03-07 CN claimed
US-9340575-B2 Agonists and antagonists of the urotensinergic system INSTITUT NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CA) 2016-05-17 US claimed
US-20150376112-A1 Photoactivatable Caged Compounds with AIE Characteristics: Method of Preparation and Applications TANG, BENZHONG (HK) 2015-12-31 US claimed
EP-2729184-A1 NOVEL AGONISTS AND ANTAGONISTS OF THE UROTENSINERGIC SYSTEM Institut National de la Recherche Scientifique (CA) 2014-05-14 EP claimed
US-20140113872-A1 NOVEL AGONISTS AND ANTAGONISTS OF THE UROTENSINERGIC SYSTEM INSTITUT NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CA) 2014-04-24 US claimed
US-8361484-B2 Polymer systems for lung volume reduction therapy AERIS THERAPEUTICS, INC. (US) 2013-01-29 US claimed
WO-2012149644-A1 NOVEL AGONISTS AND ANTAGONISTS OF THE UROTENSINERGIC SYSTEM INSTITUT NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CA) 2012-11-08 WO claimed
US-20110130522-A1 POLYMERISABLE COMPOUNDS FOR MAKING OPTO-ELECTRONIC DEVICES UNIVERSITEIT HASSELT (BE) 2011-06-02 US claimed
US-20100040538-A1 Polymer Systems for Lung Volume Reduction Therapy CANADIAN IMPERIAL BANK OF COMMERCE (CA) 2010-02-18 US claimed
EP-2059227-A2 POLYMER SYSTEMS FOR LUNG VOLUME REDUCTION THERAPY Aeris Therapeutics, Inc. (US) 2009-05-20 EP claimed
WO-2008039827-A2 POLYMER SYSTEMS FOR LUNG VOLUME REDUCTION THERAPY AERIS THERAPEUTICS, INC. (US) 2008-04-03 WO claimed