Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLOD2 | O00469 | 2/20 | 0.42 |
| ▸ | VNN1 | O95497 | 5/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | RXRB | P28702 | 1/20 | 0.38 |
| ▸ | RXRG | P48443 | 1/20 | 0.38 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PLOD3 | O60568 | 1/20 | 0.35 |
| ▸ | PLOD1 | Q02809 | 1/20 | 0.35 |
| ▸ | MLYCD | O95822 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8911336 | 0.90 | CES2 (0.52) | PLOD2CES2RXRARXRBRXRG | |
| SCHEMBL8911819 | 0.89 | PLOD2 (0.49) | PLOD2CES2HDAC3HDAC1HDAC2 | |
| SCHEMBL8912078 | 0.81 | CES2 (0.48) | PLOD2CES2RXRARXRBRXRG | |
| SCHEMBL8911872 | 0.80 | PLOD2 (0.47) | PLOD2CES2HDAC3HDAC1HDAC2 | |
| SCHEMBL8911577 | 0.79 | PLOD2 (0.46) | PLOD2CES2HDAC3HDAC1HDAC2 | |
| SCHEMBL8912767 | 0.78 | PLOD2 (0.45) | PLOD2CES2PLOD3PLOD1 | |
| SCHEMBL865889 | 0.77 | PTPN1 (0.58) | VNN1CES2RXRARXRBRXRG | |
| SCHEMBL31019373 | 0.77 | PTPN1 (0.62) | PLOD2CES2HDAC1PTPN1PLOD3 | |
| SCHEMBL6925102 | 0.77 | CES2 (0.47) | VNN1CES2RXRARXRBRXRG | |
| SCHEMBL23091848 | 0.76 | CES2 (0.55) | PLOD2CES2RXRARXRBRXRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5618547-A | ADMINISTERING PERFLUOROALKYL GROUP-CONTAINING PHENYL PROPANEDIONE DERIVATIVES | BRITISH TECHNOLOGY GROUP LIMITED (GB) | 1997-04-08 | — | — | US | disclosed |
| US-4870109-A | ANIMAL HUSBANDRY | ELI LILLY AND COMPANY (US) | 1989-09-26 | — | — | US | disclosed |