Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 4/20 | 0.36 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 3/20 | 0.34 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.34 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | IL18 | Q14116 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8577375 | 0.86 | ALDH1A1 (0.37) | CYP19A1RORCSIRT2POLBSAE1 | |
| SCHEMBL8912085 | 0.84 | CYP19A1 (0.34) | CYP19A1RORCSIRT2POLBSAE1 | |
| SCHEMBL8912796 | 0.77 | MEN1 (0.40) | CYP19A1RORCSIRT2POLBSAE1 | |
| SCHEMBL8570032 | 0.76 | ALDH1A1 (0.38) | CYP19A1RORCSIRT2POLBSAE1 | |
| SCHEMBL8913188 | 0.76 | PTGER1 (0.37) | CYP19A1RORCSIRT2MEN1KMT2A | |
| SCHEMBL8913010 | 0.75 | ALDH1A1 (0.36) | CYP19A1RORCSIRT2POLBSAE1 | |
| SCHEMBL8571774 | 0.73 | CYP11B1 (0.39) | RORCPOLBSAE1UBA2MEN1 | |
| SCHEMBL8574886 | 0.73 | ALDH1A1 (0.41) | RORCSIRT2POLBSAE1UBA2 | |
| SCHEMBL8911497 | 0.72 | PSMB5 (0.38) | RORCSIRT2POLBSAE1UBA2 | |
| SCHEMBL8911262 | 0.71 | SIRT2 (0.38) | RORCSIRT2POLBSAE1UBA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5650424-A | ANTIAGGLOMERANTS USING IMIDAZOLIDINDIONES | DR. KARL THOMAE GMBH (DE) | 1997-07-22 | — | — | US | disclosed |