Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.35 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 2/20 | 0.35 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.34 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8570032 | 0.91 | ALDH1A1 (0.38) | MEN1TP53KMT2AALDH1A1MAPT | |
| SCHEMBL8577375 | 0.91 | ALDH1A1 (0.37) | MEN1TP53KMT2AALDH1A1MAPT | |
| SCHEMBL8913188 | 0.91 | PTGER1 (0.37) | MEN1KMT2AALDH1A1MAPTCYP11B1 | |
| SCHEMBL8913010 | 0.89 | ALDH1A1 (0.36) | MEN1TP53KMT2AALDH1A1MAPT | |
| SCHEMBL8912348 | 0.87 | CYP11B1 (0.40) | MEN1TP53KMT2AALDH1A1MAPT | |
| SCHEMBL8574886 | 0.87 | ALDH1A1 (0.41) | KMT2AALDH1A1MAPTCYP11B1CYP11B2 | |
| SCHEMBL8911497 | 0.81 | PSMB5 (0.38) | ALDH1A1MAPTCYP11B1CYP11B2SIRT2 | |
| SCHEMBL8911091 | 0.81 | ALDH1A1 (0.40) | ALDH1A1MAPTCYP11B1CYP11B2SIRT2 | |
| SCHEMBL8911120 | 0.79 | NR1H2 (0.35) | ALDH1A1MAPTCYP11B1CYP11B2LMNA | |
| SCHEMBL9136606 | 0.79 | RORC (0.34) | MEN1TP53KMT2AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5650424-A | ANTIAGGLOMERANTS USING IMIDAZOLIDINDIONES | DR. KARL THOMAE GMBH (DE) | 1997-07-22 | — | — | US | disclosed |
| US-5478942-A | Antiinflammatory agents, antiagglomerants | KARL THOMAE GMBH (DE) | 1995-12-26 | — | — | US | disclosed |
| US-5276049-A | Treatment of thrombosis | DR. KARL THOMAE GMBH (DE) | 1994-01-04 | — | — | US | disclosed |