Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7281838 | 0.88 | HRH3 (0.44) | HRH3S1PR1ADRB2ADRB1HDAC1 | |
| Hydrochloric Acid SCHEMBL7275455 | 0.87 | HRH3 (0.40) | HRH3S1PR1ADRB2ADRB1HDAC1 | |
| Hydrochloric Acid SCHEMBL7282229 | 0.86 | HRH3 (0.43) | HRH3S1PR1ADRB2ADRB1HDAC1 | |
| SCHEMBL8910777 | 0.86 | HRH3 (0.39) | HRH3S1PR1ADRB2ADRB1HDAC1 | |
| SCHEMBL7283243 | 0.85 | HRH3 (0.44) | HRH3S1PR1ADRB2ADRB1HDAC1 | |
| SCHEMBL27397736 | 0.84 | MEN1 (0.51) | HRH3S1PR1HDAC1 | |
| Hydrochloric Acid SCHEMBL7272819 | 0.82 | HRH3 (0.44) | HRH3S1PR1ADRB2ADRB1HDAC1 | |
| SCHEMBL7280993 | 0.81 | HDAC1 (0.46) | HRH3S1PR1HDAC1 | |
| SCHEMBL7283131 | 0.81 | HRH3 (0.43) | HRH3S1PR1ADRB2ADRB1HDAC1 | |
| Hydrochloric Acid SCHEMBL7283462 | 0.81 | F10 (0.40) | HRH3S1PR1HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5650424-A | ANTIAGGLOMERANTS USING IMIDAZOLIDINDIONES | DR. KARL THOMAE GMBH (DE) | 1997-07-22 | — | — | US | disclosed |
| US-5478942-A | Antiinflammatory agents, antiagglomerants | KARL THOMAE GMBH (DE) | 1995-12-26 | — | — | US | disclosed |
| US-5276049-A | Treatment of thrombosis | DR. KARL THOMAE GMBH (DE) | 1994-01-04 | — | — | US | disclosed |